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Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts
Article first published online: 23 MAR 2006
DOI: 10.1002/ijc.21898
Copyright © 2006 Wiley-Liss, Inc.
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How to Cite
Saarinen, N. M., Power, K., Chen, J. and Thompson, L. U. (2006), Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts. Int. J. Cancer, 119: 925–931. doi: 10.1002/ijc.21898
Publication History
- Issue published online: 1 JUN 2006
- Article first published online: 23 MAR 2006
- Manuscript Accepted: 12 JAN 2006
- Manuscript Received: 5 OCT 2005
Funded by
- Natural Sciences and Engineering Research Council of Canada. Grant Number: A9995
- National Technology Agency of Finland. Grant Number: 40285/02
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- 2, , , , , , Antiproliferative activity of lignans against the breast carcinoma cell lines MCF 7 and BT 20, Archives of Gynecology and Obstetrics, 2011, 285, 4, 1145
- 3, , , , Risks and benefits of dietary isoflavones for cancer, Critical Reviews in Toxicology, 2011, 41, 6, 463
- 4, , , , The intestinal microbiome: A separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals, Fitoterapia, 2011, 82, 1, 53
- 5, , , , , Effects of isoflavones on breast density in pre- and post-menopausal women: a systematic review and meta-analysis of randomized controlled trials, Human Reproduction Update, 2010, 16, 6, 745
- 6, , , , Flaxseed cotyledon fraction reduces tumour growth and sensitises tamoxifen treatment of human breast cancer xenograft (MCF-7) in athymic mice, British Journal of Nutrition, 2010, 105, 03, 339
- 7, , , Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen, Molecular Nutrition & Food Research, 2010, 54, 10Direct Link:
- 8, , , , , , , , , , , Dietary lignan intakes in relation to survival among women with breast cancer: the Western New York Exposures and Breast Cancer (WEB) Study, Breast Cancer Research and Treatment, 2009, 122, 1, 229
- 9, , , , , , Dietary sources of lignans and isoflavones modulate responses to estradiol in estrogen reporter mice, Molecular Nutrition & Food Research, 2009, 53, 8Direct Link:
- 10, , , , , , , , , , , Low Dose Estrogen Supplementation Reduces Mortality of Mice in Estrogen-Dependent Human Tumor Xenograft Model, Biological & Pharmaceutical Bulletin, 2009, 32, 1, 150
- 11, , Oestrogenicity of prenylflavonoids from hops: activation of pro-oestrogens by intestinal bacteria, Environmental Microbiology Reports, 2009, 1, 2Direct Link:
- 12, , , , Changes in biomarkers of estrogen receptor and growth factor signaling pathways in MCF-7 tumors after short- and long-term treatment with soy and flaxseed, The Journal of Steroid Biochemistry and Molecular Biology, 2008, 112, 1-3, 13
- 13, , Can the combination of flaxseed and its lignans with soy and its isoflavones reduce the growth stimulatory effect of soy and its isoflavones on established breast cancer?, Molecular Nutrition & Food Research, 2007, 51, 7Direct Link:
- 14, , , , , Dietary Flaxseed Interaction With Tamoxifen Induced Tumor Regression in Athymic Mice With MCF-7 Xenografts by Downregulating the Expression of Estrogen Related Gene Products and Signal Transduction Pathways, Nutrition and Cancer, 2007, 58, 2, 162
- 15, , Differential effects of soybean and fenugreek extracts on the growth of MCF-7 cells, Chemico-Biological Interactions, 2007, 170, 2, 135
- 16, , , , , Flaxseed and Soy Protein Isolate, Alone and in Combination, Differ in their Effect on Bone Mass, Biomechanical Strength, and Uterus in Ovariectomized Nude Mice with MCF-7 Human Breast Tumor Xenografts, Journal of Toxicology and Environmental Health, Part A, 2007, 70, 22, 1888
- 17, , , Addressing the Soy and Breast Cancer Relationship: Review, Commentary, and Workshop Proceedings, JNCI Journal of the National Cancer Institute, 2006, 98, 18, 1275

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