Epidemiology

You have full text access to this OnlineOpen article

Prevalence and determinants of human papillomavirus infection in men attending vasectomy clinics in Mexico

  1. Salvatore Vaccarella1,
  2. Eduardo Lazcano-Ponce2,†,*,
  3. José Antonio Castro-Garduño3,
  4. Aurelio Cruz-Valdez2,
  5. Vicente Díaz4,
  6. Rafaela Schiavon3,
  7. Pilar Hernández2,
  8. Janet R. Kornegay5,
  9. Mauricio Hernández-Avila2,
  10. Silvia Franceschi1

Article first published online: 17 MAY 2006

DOI: 10.1002/ijc.21992

Issue

International Journal of Cancer

International Journal of Cancer

Volume 119, Issue 8, pages 1934–1939, 15 October 2006

Additional Information

How to Cite

Vaccarella, S., Lazcano-Ponce, E., Castro-Garduño, J. A., Cruz-Valdez, A., Díaz, V., Schiavon, R., Hernández, P., Kornegay, J. R., Hernández-Avila, M. and Franceschi, S. (2006), Prevalence and determinants of human papillomavirus infection in men attending vasectomy clinics in Mexico. Int. J. Cancer, 119: 1934–1939. doi: 10.1002/ijc.21992

Author Information

  1. 1

    International Agency for Research on Cancer, Lyon, France

  2. 2

    Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico

  3. 3

    Dirección General de Equidad y Género en Salud, Dirección de Salud Reproductiva, Mexico City, Mexico

  4. 4

    Fundación Mexicana para la Planeación Familiar, Mexico City, Mexico

  5. 5

    Roche Molecular Systems, Inc., Alameda, CA

  1. †

    Fax: +52-777-311-11-48.

*Centro de Investigaciones en Salud Poblacional, Instituto Nacional de Salud Pública, Av. Universidad 655, Col. Sta Maria, Ahuacatitlan, C.P. 62508 Cuernavaca, Morelos, Mexico

Publication History

  1. Issue published online: 11 AUG 2006
  2. Article first published online: 17 MAY 2006
  3. Manuscript Accepted: 1 MAR 2006
  4. Manuscript Received: 13 JAN 2006

Funded by

  • Mexican National Science and Technology Council (Consejo Nacional de Ciencia y Tecnología, CONACYT). Grant Numbers: SALUD-2002-C01-7800, 34468-M
  • International Agency for Research on Cancer. Grant Numbers: FI/92/3-5 MEX-4, FIS/03/02
  • Instituto Nacional de Salud Pública

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (121K)

Keywords:

  • human papillomavirus;
  • men;
  • Mexico;
  • sexual habits;
  • condom use

Abstract

Large studies of genital human papillomavirus (HPV) infection in men are few and mainly include high-risk groups. We interviewed 779 men who requested a vasectomy in 27 public clinics in 14 states of Mexico. Exfoliated cells were obtained from the scrotum, the shaft of the penis, the top of the penis including the coronal sulcus, the glans and the opening of the meatus. HPV testing was performed using biotinylated L1 consensus primers and reverse line blot. Unconditional logistic regression was used to estimate odds ratios (ORs) of being HPV-positive and corresponding 95% confidence intervals (CIs). The prevalence of any type of HPV was 8.7%. HPV positivity was highest among men below age 25 (13.6%), and lowest among men aged 40 years or older (6.0%). The most commonly found HPV types were, in decreasing order, HPV59, 51, 6, 16 and 58. Lifetime number of sexual partners was associated with HPV positivity (OR for ≥4 vs. 1 partner = 3.7, 95% CI: 2.0–6.8), mainly on account of the strong association with number of occasional and sex-worker partners. Condom use with both regular (OR = 0.4, 95% CI: 0.1–1.0) and sex-worker (OR = 0.1, 95% CI: 0.0–0.3) partners and circumcision (OR = 0.2, 95% CI: 0.1–0.4) were inversely associated with HPV positivity. HPV prevalence in Mexican men was similar to the prevalence found in Mexican women of the same age groups. The association between HPV positivity and lifetime number of sexual partners in the present low-risk male population is one of the strongest ever reported in studies in men. Condom use and circumcision were associated with a strong reduction in HPV prevalence. © 2006 Wiley-Liss, Inc.

View Full Article (HTML) Get PDF (121K)