Tumor Immunology

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TAP expression reduces IL-10 expressing tumor infiltrating lymphocytes and restores immunosurveillance against melanoma

  1. Qian-Jin Zhang1,†,‡,
  2. Robyn P. Seipp1,2,3,‡,
  3. Susan S. Chen1,2,3,‡,
  4. Timothy Z. Vitalis1,
  5. Xiao-Lin Li1,†,
  6. Kyung-Bok Choi1,2,
  7. Andrew Jeffries1,2,
  8. Wilfred A. Jefferies1,2,3,4,5,*

Article first published online: 2 FEB 2007

DOI: 10.1002/ijc.22371

Issue

International Journal of Cancer

International Journal of Cancer

Volume 120, Issue 9, pages 1935–1941, 1 May 2007

Additional Information

How to Cite

Zhang, Q.-J., Seipp, R. P., Chen, S. S., Vitalis, T. Z., Li, X.-L., Choi, K.-B., Jeffries, A. and Jefferies, W. A. (2007), TAP expression reduces IL-10 expressing tumor infiltrating lymphocytes and restores immunosurveillance against melanoma. Int. J. Cancer, 120: 1935–1941. doi: 10.1002/ijc.22371

Author Information

  1. 1

    Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada

  2. 2

    Biomedical Research Centre, University of British Columbia, Vancouver, BC, Canada

  3. 3

    Department of Zoology, University of British Columbia, Vancouver, BC, Canada

  4. 4

    Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada

  5. 5

    Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada

  1. †

    Department of Cellular Biology and Anatomy, Gene Therapy Program, Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, LA USA 71103

  1. ‡

    First three authors contributed equally to this work.

*Biomedical Research Center and the Michael Smith Laboratories, 2222 Health Sciences Mall, University of British Columbia, Vancouver, British Columbia, V6T 1Z3 Canada

Publication History

  1. Issue published online: 28 FEB 2007
  2. Article first published online: 2 FEB 2007
  3. Manuscript Accepted: 4 SEP 2006
  4. Manuscript Received: 28 SEP 2005

Funded by

  • CANVAC
  • CIHR
  • NCIC
  • GeneMax Pharmaceuticals

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