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Cancer Cell Biology
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Pathogenesis and vascular integrity of breast cancer brain metastasis
Article first published online: 22 DEC 2006
DOI: 10.1002/ijc.22388
Copyright © 2006 Wiley-Liss, Inc.
Additional Information
How to Cite
Lu, W., Bucana, C. D. and Schroit, A. J. (2007), Pathogenesis and vascular integrity of breast cancer brain metastasis. Int. J. Cancer, 120: 1023–1026. doi: 10.1002/ijc.22388
Publication History
- Issue published online: 19 JAN 2007
- Article first published online: 22 DEC 2006
- Manuscript Accepted: 22 AUG 2006
- Manuscript Received: 15 MAY 2006
Funded by
- U.S. Department of Defense. Grant Numbers: W81XWH-04-1-0628, PC030875
- National Institutes of Health. Grant Number: CA98527
- John Q. Gaines Foundation
References
- 1,,,,,,,,,,,, et al. Brain metastases—epidemiologic features of brain metastases. Curr Prob Surg 2004; 41: 665–741.
- 2,,,. Pathobiology of brain metastases. J Clin Pathol 2005; 58: 237–42.
- 3,,. The pathogenesis and treatment of brain metastases: a comprehensive review. Crit Rev Oncol-Hematol 2004; 52: 199–215.
- 4,. Management of brain metastases. Semin Oncol 2004; 31: 693–701.
- 5,,,,. Arrest and extravasation of B-16 amelanotic melanoma in murine lungs—a light and electron-microscopic study. Lab Invest 1985; 53: 470–8.
- 6,,,,. Morphological-study of the interaction of intravascular tumor-cells with endothelial-cells and subendothelial matrix. Cancer Res 1988; 48: 4065–72.
- 7
- 8,,,,,. Controversies in the management of brain metastases: the role of chemotherapy. Forum 2001; 11: 59–74.
- 9
- 10. Biology of a brain metastasis. Neurosurg Clin N Am 1996; 7: 369–76.
- 11,,. Blood-brain barrier permeability of human gliomas as determined by quantitation of cytoplasmic vesicles of the capillary endothelium and scintigraphic findings. Cancer Invest 1989; 7: 313–21.
- 12,,,. Quantitative study of microvessel ultrastructure in human peritumoral brain-tissue—evidence for a blood-brain-barrier defect. J Neurosurg 1987; 67: 697–705.
- 13,,,,. Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice. Am J Pathol 1992; 141: 1115–24.
- 14,,,,,. Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis. Nat Med 2000; 6: 100–2.
- 15. Critical factors in the biology of human cancer metastasis—twenty-eighth Clowes G.H.A. memorial award lecture. Cancer Res 1990; 50: 6130–8.
- 16,,,,,,,,. Fate of melanoma-cells entering the microcirculation—over 80-percent survive and extravasate. Cancer Res 1995; 55: 2520–3.
- 17. Orthotopic transplant mouse models with green fluorescent protein-expressing cancer cells to visualize metastasis and angiogenesis. Cancer Metast Rev 1998; 17: 271–7.
- 18,,,,,,,,,. Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system. Cancer Res 2006; 66: 4208–14.
- 19,,. Treatment of metastatic cancer. In: DeVitaJBT,HellmanS,RosenbergSA, eds. Cancer: principles and practice of oncology. Lippincott-Raven, New York, NY 2006. 2523–2606.

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