Fax: +353-1-2696018.
Early Detection and Diagnosis
You have full text access to this OnlineOpen article
Lipophilin B: A gene preferentially expressed in breast tissue and upregulated in breast cancer
Article first published online: 12 DEC 2006
DOI: 10.1002/ijc.22471
Copyright © 2006 Wiley-Liss, Inc.
Additional Information
How to Cite
Culleton, J., O'Brien, N., Ryan, B. M., Hill, A. D.K., McDermott, E., O'Higgins, N. and Duffy, M. J. (2007), Lipophilin B: A gene preferentially expressed in breast tissue and upregulated in breast cancer. Int. J. Cancer, 120: 1087–1092. doi: 10.1002/ijc.22471
Publication History
- Issue published online: 19 JAN 2007
- Article first published online: 12 DEC 2006
- Manuscript Accepted: 5 OCT 2006
- Manuscript Received: 16 MAY 2006
Funded by
- Irish Research Council for Science Engineering and Technology
- Irish Cancer Society
- Health Research Board of Ireland
- Programme Grant, Breast Cancer Metastasis: Biomarkers and Functional Mediators
References
- 1, , , , , , , , . Uterglobin/Clara cell 10 kDa family of proteins: nomenclature committee report. Ann NY Acad Sci 2000; 923: 348–54.Direct Link:
- 2, , , . INF-γ stimulates the expression of a novel secretoglobin that regulates chemotactic cell migration and invasion. J Immunol 2004; 172: 4245–52.
- 3, , , , . Structure and transcriptional regulation of the human mammaglobin gene, a breast cancer associated member of the uteroglobin gene family localized to chromosome 11q13. Oncogene 1998; 16: 817–24.
- 4, . Mammaglobin: a candidate diagnostic marker for breast cancer. Clin Biochem 2004; 37: 249–57.
- 5, . Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer. Cancer Res 1996; 56: 860–5.
- 6, , , , , , . Mammaglobin expression in primary, metastatic and occult breast cancer. Cancer Res 1999; 59: 3028–31.
- 7, , , , , , , , , . Discovery of differentially expressed genes in human breast cancer using subtracted cDNA libraries and cDNA microarrays. Oncogene 2002; 21: 2270–82.
- 8, , , , , , , . Mammaglobin A: a promising marker for breast cancer. Clin Chem 2002; 48: 1362–4.
- 9, , , , , , , , , , . Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer. Biochemistry 2002; 41: 6714–22.
- 10, , , , , , . Mammaglobin A in breast cancer: existence of multiple molecular forms. Int J Cancer 2005; 114: 623–7.Direct Link:
- 11, , , , , , , , , , , , et al. Transcriptional complementarity in breast cancer: application to detection of circulating tumor cells. Mol Diagn 2001; 6: 79–91.
- 12, , , , , , , , , . Mammaglobin is found in breast tissue as a complex with BU101. Biochemistry 2001; 40: 11048–59.
- 13, , , , , , . Expression of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveal their coexpression in gynaecologic malignancies. BMC Cancer 2006; 6: 88.
- 14, . Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156–9.
- 15, , , , , . Studies on oestrogen receptor-α and-β mRNA in breast cancer. Eur J Cancer 2001; 37: 1118–22.
- 16, , , , , , , . Mammaglobin is associated with low grade, steroid receptor-positive breast tumours from postmenopausal patients, and has independent prognostic value for relapse-free survival time. J Clin Oncol 2004; 22: 691–8.
- 17, , , , , , . Identification of mammaglobin as a novel serum marker for breast cancer. Clin Cancer Res 2005; 11: 6528–35.
- 18, , , , , , , , , , . Mammaglobin as a novel breast cancer biomarker: multigene reverse transcription-PCR assay and sandwich ELISA. Clin Chem 2004; 50: 2069–76.
- 19, , , , , , , , , , , . Serum antibodies to lipophilin B detected in late stage breast cancer patients. Clin Cancer Res 2003; 9: 749–54.

1097-0215/asset/olbannerleft.jpg?v=1&s=45719cd7de57873027993264fcc568b335a8cd56)
1097-0215/asset/olbannerright.jpg?v=1&s=5e0fba63c1309b3036eb9215a0e1e83dd02efd19)
1097-0215/asset/cover.gif?v=1&s=9bea5e55449dab2cff7ad3b06277cc9745417a23)