Infectious Causes of Cancer

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Chlamydophila psittaci is viable and infectious in the conjunctiva and peripheral blood of patients with ocular adnexal lymphoma: Results of a single-center prospective case–control study

  1. Andrés J.M. Ferreri1,2,†,*,
  2. Riccardo Dolcetti3,
  3. Giuseppina P. Dognini1,2,
  4. Lucia Malabarba4,
  5. Nadia Vicari5,
  6. Elisa Pasini3,
  7. Maurilio Ponzoni1,6,
  8. Maria Giulia Cangi6,
  9. Lorenza Pecciarini6,
  10. Antonio Giordano Resti7,
  11. Claudio Doglioni1,6,
  12. Silvano Rossini4,
  13. Simone Magnino4

Article first published online: 4 JUN 2008

DOI: 10.1002/ijc.23596

Issue

International Journal of Cancer

International Journal of Cancer

Volume 123, Issue 5, pages 1089–1093, 1 September 2008

Additional Information

How to Cite

Ferreri, A. J.M., Dolcetti, R., Dognini, G. P., Malabarba, L., Vicari, N., Pasini, E., Ponzoni, M., Cangi, M. G., Pecciarini, L., Resti, A. G., Doglioni, C., Rossini, S. and Magnino, S. (2008), Chlamydophila psittaci is viable and infectious in the conjunctiva and peripheral blood of patients with ocular adnexal lymphoma: Results of a single-center prospective case–control study. Int. J. Cancer, 123: 1089–1093. doi: 10.1002/ijc.23596

Author Information

  1. 1

    Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy

  2. 2

    Medical Oncology Unit, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy

  3. 3

    Cancer Bio-Immunotherapy Unit, Department of Medical Oncology, Centro di Riferimento Oncologico, IRCCS National Cancer Institute, Aviano, Italy

  4. 4

    Servizio di Immunoematologia e Medicina Trasfusionale, San Raffaele Scientific Institute, Milan, Italy

  5. 5

    National Reference Laboratory for Animal Chlamydioses, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Pavia, Italy

  6. 6

    Pathology Unit, San Raffaele Scientific Institute, Milan, Italy

  7. 7

    Ophthalmology Unit, San Raffaele Scientific Institute, Milan, Italy

  1. †

    Fax: +0039-02-26437625.

*Unit of Lymphoid Malignancies, Medical Oncology Unit, Department of Oncology, San Raffaele H Scientific Institute, Via Olgettina 60, 20132-Milan, Italy

Publication History

  1. Issue published online: 17 JUN 2008
  2. Article first published online: 4 JUN 2008
  3. Manuscript Accepted: 5 MAR 2008
  4. Manuscript Received: 9 JAN 2008

Funded by

  • Italian Association for Cancer Research (AIRC)

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References

  • 1
    Ferreri AJ,Guidoboni M,Ponzoni M,De Conciliis C,Dell'Oro S,Fleischhauer K,Caggiari L,Lettini AA,Dal Cin E,Ieri R,Freschi M,Villa E, et al. Evidence for an association between chlamydia psittaci and ocular adnexal lymphomas. J Natl Cancer Inst 2004; 96: 586–94.
  • 2
    Bush RM,Everett KD. Molecular evolution of the chlamydiaceae. Int J Syst Evol Microbiol 2001; 51: 203–20.
  • 3
    Peeling RW,Brunham RC. Chlamydiae as pathogens: new species and new issues. Emerg Infect Dis 1996; 2: 307–19.
  • 4
    Ferreri AJ,Ponzoni M,Guidoboni M,Resti AG,Politi LS,Cortelazzo S,Demeter J,Zallio F,Palmas A,Muti G,Dognini GP,Pasini E, et al. Bacteria-eradicating therapy with doxycycline in ocular adnexal MALT lymphoma: a multicenter prospective trial. J Natl Cancer Inst 2006; 98: 1375–82.
  • 5
    Ferreri AJ,Ponzoni M,Guidoboni M,De Conciliis C,Resti AG,Mazzi B,Lettini AA,Demeter J,Dell'Oro S,Doglioni C,Villa E,Boiocchi M, et al. Regression of ocular adnexal lymphoma after Chlamydia psittaci-eradicating antibiotic therapy. J Clin Oncol 2005; 23: 5067–73.
  • 6
    Du MQ. MALT lymphoma: recent advances in aetiology and molecular genetics. J Clin Exp Hematop 2007; 47: 31–42.
  • 7
    Isaacson PG. Gastric MALT lymphoma: from concept to cure. Ann Oncol 1999; 10: 637–45.
  • 8
    Ossewaarde JM,Meijer A. Molecular evidence for the existence of additional members of the order chlamydiales. Microbiology 1999; 145(Part 2): 411–7.
  • 9
    Madico G,Quinn TC,Boman J,Gaydos CA. Touchdown enzyme time release-PCR for detection and identification of chlamydia trachomatis, C. pneumoniae, and C. psittaci using the 16S and 16S-23S spacer rRNA genes. J Clin Microbiol 2000; 38: 1085–93.
  • 10
    Hill JE,Goh SH,Money DM,Doyle M,Li A,Crosby WL,Links M,Leung A,Chan D,Hemmingsen SM. Characterization of vaginal microflora of healthy, nonpregnant women by chaperonin-60 sequence-based methods. Am J Obstet Gynecol 2005; 193(3 Part 1): 682–92.
  • 11
    Koivisto AL,Isoaho R,Von Hertzen L,Toyryla M,Laippala P,Kivela SL,Saikku P. Chlamydial antibodies in an elderly Finnish population. Scand J Infect Dis 1999; 31: 135–9.
  • 12
    Kaleta EF,Taday EM. Avian host range of chlamydophila spp. based on isolation, antigen detection and serology. Avian Pathol 2003; 32: 435–61.
  • 13
    Cirino F,Webley WC,West C,Croteau NL,Andrzejewski C,Jr,Stuart ES. Detection of chlamydia in the peripheral blood cells of normal donors using in vitro culture, immunofluorescence microscopy and flow cytometry techniques. BMC Infect Dis 2006; 10;6: 23.
  • 14
    Beatty WL,Morrison RP,Byrne GI. Persistent chlamydiae: From cell culture to a paradigm for chlamydial pathogenesis. Microbiol Rev 1994; 58: 686–99.
  • 15
    Gerard HC,Whittum-Hudson JA,Schumacher HR,Hudson AP. Differential expression of three chlamydia trachomatis hsp60-encoding genes in active vs. persistent infections. Microb Pathog 2004; 36: 35–9.
  • 16
    Nasisse MP,Guy JS,Stevens JB,English RV,Davidson MG. Clinical and laboratory findings in chronic conjunctivitis in cats: 91 cases (1983–1991). J Am Vet Med Assoc 1993; 203: 834–7.
  • 17
    Lietman T,Brooks D,Moncada J,Schachter J,Dawson C,Dean D. Chronic follicular conjunctivitis associated with chlamydia psittaci or chlamydia pneumoniae. Clin Infect Dis 1998; 26: 1335–40.
  • 18
    Ferreri AJ,Dolcetti R,Magnino S,Doglioni C,Cangi MG,Pecciarini L,Ghia P,Dagklis A,Pasini E,Vicari N,Dognini GP,Giordano Resti A, et al. A woman and her canary: a tale of chlamydiae and lymphomas. J Natl Cancer Inst 2007; 99: 1418–9.
  • 19
    Grimes JE. Avian chlamydiosis. In: BeranGW,SteeleJH, eds. CRC handbook of zoonoses,2nd ed. Boca Raton: CRC Press, 1994; 389–402.
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