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Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK)

  1. Yolanda Sánchez1,
  2. Donna Amrán1,2,
  3. Carlos Fernández1,
  4. Elena de Blas1,
  5. Patricio Aller1,†,*

Article first published online: 10 JUN 2008

DOI: 10.1002/ijc.23639

Issue

International Journal of Cancer

International Journal of Cancer

Volume 123, Issue 5, pages 1205–1214, 1 September 2008

Additional Information

How to Cite

Sánchez, Y., Amrán, D., Fernández, C., de Blas, E. and Aller, P. (2008), Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK). Int. J. Cancer, 123: 1205–1214. doi: 10.1002/ijc.23639

Author Information

  1. 1

    Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain

  2. 2

    Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense, Madrid, Spain

  1. †

    Fax: +34-915360432

*Centro de Investigaciones Biológicas, CSIC. Ramiro de Maeztu 9, 28040 Madrid, Spain

Publication History

  1. Issue published online: 17 JUN 2008
  2. Article first published online: 10 JUN 2008
  3. Manuscript Accepted: 17 MAR 2008
  4. Manuscript Revised: 26 FEB 2008
  5. Manuscript Received: 18 NOV 2007

Funded by

  • Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica, Dirección General de Investigación, Ministerio de Educación y Ciencia, Spain. Grant Numbers: SAF2004-01250, SAF2007-64721
  • Spain/Greece Joint Research and Technology. Grant Number: HG2005-0036
  • Plan de Formación de Personal Investigador, Ministerio de Educación y Ciencia, Spain
  • Universidad Complutense de Madrid, Spain

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