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Additional Supporting Information may be found in the online version of this article.

FilenameFormatSizeDescription
IJC_24194_sm_suppfig1.tif19231KSupporting Figure 1. Unsupervised hierarchical clustering. A. 111 laser microdissected tissue samples were classified based on the fluorescence intensity of 3623 identified protein spots. B. The same samples were classified based on the fluorescence intensity of 200 protein spots with considerable difference of intensity between the normal and the cancer tissues examined (FDR [lt] 0.001 and fold difference [mt] 4). 33 spots showed increased and 167 spots showed decreased expression in tumor tissues.
IJC_24194_sm_suppfig2.tif27117KSupporting Figure 2. Enlarged 2D image of the Cy3-labeled internal control sample. The intensity of 22 protein spots was significantly different between the two sample groups. The numbers correspond to those in Figure 2B, Table 3, and Supplemental Table 4. A concise image is demonstrated in Figure 2A.
IJC_24194_sm_suppfig3.tif24020KSupporting Figure 3. Enlarged image of Fig. 3A showing both cytoplasmic and nuclear immunohistochemical staining of the ESCC tumor tissues examined for TGM3.
IJC_24194_sm_supptable1.xls31KSupporting Supplementary Table 1. Summary of the individual clinicopathological characteristics of the 82 cases analyzed.
IJC_24194_sm_supptable2.xls22KSupporting Supplementary Table 2. Summary of the tissue examined using the tissue microarray.
IJC_24194_sm_supptable3.xls850KSupporting Supplementary Table 3. Detailed data of 200 identified proteins with significantly different intensity between the cancer and normal tissues.
IJC_24194_sm_supptable4.tif679KSupporting Supplementary Table 4. Detailed data of the 22 identified proteins with significantly different intensity between the two prognosis groups.

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