Recent patterns in gastric cancer: A global overview

Authors

  • Paola Bertuccio,

    1. Istituto di Ricerche Farmacologiche “Mario Negri”, Via G. La Masa 19, 20156 Milan, Italy
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  • Liliane Chatenoud,

    Corresponding author
    1. Istituto di Ricerche Farmacologiche “Mario Negri”, Via G. La Masa 19, 20156 Milan, Italy
    • Istituto di Ricerche Farmacologiche “Mario Negri”, Via Giuseppe La Masa 19, 20156 Milan, Italy
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    • Fax: +39-0233200231.

  • Fabio Levi,

    1. Unite' d'Épidemiologie du Cancer et Registres Vaudois et Neuchâtelois des Tumeurs, Institut de Médecine Sociale et Préventive (IUMSP), Centre Hospitalier Universitaire Vaudois et Universite' de Lausanne, CHUV-Falaises 1, 1011 Lausanne, Switzerland
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  • Delphine Praud,

    1. Istituto di Ricerche Farmacologiche “Mario Negri”, Via G. La Masa 19, 20156 Milan, Italy
    2. Institut d'Informatique et de Mathématiques Appliquées, Université Joseph Fourier, BP N°53, 38041 Grenoble Cedex 9, France
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  • Jacques Ferlay,

    1. International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France
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  • Eva Negri,

    1. Istituto di Ricerche Farmacologiche “Mario Negri”, Via G. La Masa 19, 20156 Milan, Italy
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  • Matteo Malvezzi,

    1. Istituto di Ricerche Farmacologiche “Mario Negri”, Via G. La Masa 19, 20156 Milan, Italy
    2. Istituto di Statistica Medica e Biometria “G.A. Maccacaro”, Università degli Studi di Milano, Via Venezian 1, 20133 Milan, Italy
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  • Carlo La Vecchia

    1. Istituto di Ricerche Farmacologiche “Mario Negri”, Via G. La Masa 19, 20156 Milan, Italy
    2. Istituto di Statistica Medica e Biometria “G.A. Maccacaro”, Università degli Studi di Milano, Via Venezian 1, 20133 Milan, Italy
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Abstract

Until the mid-1990s, gastric cancer has been the first cause of cancer death worldwide, although rates had been declining for several decades and gastric cancer has become a relatively rare cancer in North America and in most Northern and Western Europe, but not in Eastern Europe, Russia and selected areas of Central and South America or East Asia. We analyzed gastric cancer mortality in Europe and other areas of the world from 1980 to 2005 using joinpoint regression analysis, and provided updated site-specific incidence rates from 51 selected registries. Over the last decade, the annual percent change (APC) in mortality rate was around −3, −4% for the major European countries. The APC were similar for the Republic of Korea (APC = −4.3%), Australia (−3.7%), the USA (−3.6%), Japan (−3.5%), Ukraine (−3%) and the Russian Federation (−2.8%). In Latin America, the decline was less marked, but constant with APC around −1.6% in Chile and Brazil, −2.3% in Argentina and Mexico and −2.6% in Colombia. Cancers in the fundus and pylorus are more common in high incidence and mortality areas and have been declining more than cardia gastric cancer. Steady downward trends persist in gastric cancer mortality worldwide even in middle aged population, and hence further appreciable declines are likely in the near future. © 2009 UICC

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