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Early Detection and Diagnosis
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Fiber diffraction of skin and nails provides an accurate diagnosis of malignancies
Article first published online: 3 FEB 2009
DOI: 10.1002/ijc.24313
Copyright © 2009 UICC
Additional Information
How to Cite
James, V. J. (2009), Fiber diffraction of skin and nails provides an accurate diagnosis of malignancies. International Journal of Cancer, 125: 133–138. doi: 10.1002/ijc.24313
Publication History
- Issue published online: 27 APR 2009
- Article first published online: 3 FEB 2009
- Accepted manuscript online: 3 FEB 2009 12:00AM EST
- Manuscript Accepted: 16 JAN 2009
- Manuscript Received: 4 NOV 2008
Funded by
- Whittington Hospital Postgraduate Research Fund
- The Courthouse Collection, Western Australia
- Commonwealth of Australia (Access to Major Research Facilities Program, Australian Synchrotron Research Program)
- US Department of Energy, Basic Energy Sciences, Office of Science. Grant Number: W-31-109-ENG-38 W-31-109-Eng-38
- Abstract
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Keywords:
- cancer diagnosis;
- fiber diffraction;
- skin;
- nails
Abstract
An early diagnosis of malignancies correlates directly with a better prognosis. Yet for many malignancies there are no readily available, noninvasive, cost-effective diagnostic tests with patients often presenting too late for effective treatment. This article describes for the first time the use of fiber diffraction patterns of skin or fingernails, using X-ray sources, as a biometric diagnostic method for detecting neoplastic disorders including but not limited to melanoma, breast, colon and prostate cancers. With suitable further development, an early low-cost, totally noninvasive yet reliable diagnostic test could be conducted on a regular basis in local radiology facilities, as a confirmatory test for other diagnostic procedures or as a mass screening test using suitable small angle X-ray beam-lines at synchrotrons. © 2009 UICC