• 1
    Weissleder R,Mahmood U. Molecular imaging. Radiology 2001; 219: 31633.
  • 2
    Schulze-Garg C,Löhler J,Gocht A,Deppert W. A transgenic mouse model for the ductal carcinoma in situ (DCIS) of the mammary gland. Oncogene 2000; 19: 102837.
  • 3
    Krepulat F,Löhler J,Heinlein C,Hermannstädter A,Tolstonog GV,Deppert W. Epigenetic mechanisms affect mutant p53 transgene expression in WAP-mutp53 transgenic mice. Oncogene 2005; 24: 464559.
  • 4
    Heinlein C,Krepulat F,Löhler J,Speidel D,Deppert W,Tolstonog GV. Mutant p53(R270H) gain of function phenotype in a mouse model for oncogene-induced mammary carcinogenesis. Int J Cancer 2008; 122: 17019.
  • 5
    Voorhoeve PMAgami R. The tumor-suppressive functions of the human INK4A locus. Cancer Cell 2003; 4: 31119.
  • 6
    Chen W,Possemato R,Campbell KT,Plattner CA,Pallas DC,Hahn WC. Identification of specific PP2A complexes involved in human cell transformation. Cancer Cell 2004; 5: 12736.
  • 7
    Schmidt KF,Ziu M,Schmidt NO,Vaghasia P,Cargioli TG,Doshi S,Albert MS,Black PM,Carroll RS,Sun Y. Volume reconstruction techniques improve the correlation between histological and in vivo tumor volume measurements in mouse models of human gliomas. J Neurooncol 2004; 68: 20715.
  • 8
    McCarville MB,Streck CJ,Dickson PV,Li CS,Nathwani AC,Davidoff AM. Angiogenesis inhibitors in a murine neuroblastoma model: quantitative assessment of intratumoral blood flow with contrast-enhanced grey-scale US. Radiology 2006; 240: 7381.
  • 9
    Wu G,Wang L,Yu L,Wang H,Xuan JW. The use of three-dimensional ultrasound micro-imaging to monitor prostate tumor development in a transgenic prostate cancer mouse model. Tohoku J Exp Med 2005; 207: 1819.
  • 10
    Wirtzfeld LA,Wu G,Bygrave M,Yamasaki Y,Sakai H,Moussa M,Izawa JI,Downey DB,Greenberg NM,Fenster A,Xuan JW,Lacefield JC. A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model. Cancer Res 2005; 65: 52317.
  • 11
    Cavanough D,Johnson E,Price RE,Kurie J,Travis EL,Cody DD. Invivo respiratory-gated micro-CT imaging in small animal oncology models. Mol Imaging 2004; 3: 5562.
  • 12
    Yang Y,Tai YC,Siegel S,Newport DF,Bai B,Li Q,Leahy RM,Cherry SR. Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging. Phys Med Bio 2004; 49: 252745.
  • 13
    Del Guerra A,Belcari N. Advances in animal PET scanners. Q J Nucl Med 2002; 46: 3547.
  • 14
    Ford NL,Thornton MM,Holdsworth DW. Fundamental image quality limits for microcomputed tomography in small animals. Med Phys 2003; 30: 286977.
  • 15
    Kalender WA,Kyriakou Y. Flat-detector computed tomography (FD-CT). Eur Radiol 2007; 17: 276779.
  • 16
    Boone JM,Velazquez O,Cherry SR. Small-animal X-ray dose from micro-CT. Mol Imaging 2004; 3: 14958.
  • 17
    Greschus S,Kiessling F,Lichy MP,Moll J,Mueller MM,Savai R,Rose F,Ruppert C,Günther A,Luecke M,Fusenig NE,Semmler W, et al. Potential applications of flat-panel volumetric CT in morphologic and functional small animal imaging. Neoplasia 2005; 7: 73040.
  • 18
    Kiessling F,Greschus S,Lichy MP,Bock M,Fink C,Vosseler S,Moll J,Mueller MM,Fusenig NE,Traupe H,Semmler W. Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis. Nat Med 2004; 10: 11338.
  • 19
    Missbach-Guentner J,Dullin C,Kimmina S,Zientkowska M,Domeyer-Missbach M,Malz C,Grabbe E,Stühmer W,Alves F. Morphological changes of mammary carcinomas in mice over time as monitored by Flat-Panel Detector Volume Computed Tomography. Neoplasia 2008; 10: 66373.
  • 20
    Obenauer S,Dullin C,Alves F,Missbach-Guentner J,Grabbe E,Heuser M. Flat-panel-detector-based volumetric CT: performance evaluation of imaging for skeletal structures of small animals in comparison to multislice CT. Clin Imaging 2007; 31: 1822.
  • 21
    Dullin C,Missbach-Guentner J,Vogel WF,Grabbe E,Alves F. Semi-automatic classification of skeletal morphology in genetically altered mice using Flat-panel Volume Computed Tomography. PloS Genet 2007; 20: e118.
  • 22
    Missbach-Guentner J,Dullin C,Zientkowska M,Domeyer-Missbach M,Kimmina S,Obenauer S,Kauer F,Stühmer W,Grabbe E,Vogel WF,Alves F. Flat-panel detector based fpVCT: a novel 3D imaging technique to monitor osteolytic bone lesions in a mouse tumor metastasis model. Neoplasia 2007; 9: 75565.
  • 23
    Ecke I,Rosenberger A,Obenauer S,Dullin C,Aberger F,Kimmina S,Schweyer S,Hahn H. Cyclopamine treatment of full-blown Hh/Ptch-associated RMS partially inhibits Hh/Ptch signaling, but not tumor growth. Mol Carcinog 2008; 47: 36172.
  • 24
    Sickles EA. Periodic mammographic follow-up of probably benign lesions: results in 3,184 consecutive cases. Radiology 1991; 179: 4638.
  • 25
    Jeswani T,Padhani AR. Imaging tumor angiogenesis. Cancer Imaging 2005; 5: 1318.
  • 26
    McDonald DM,Choyke PL. Imaging of angiogenesis: from microscope to clinic. Nat Med 2003; 9: 71325.
  • 27
    Zhang M,Kono M. Solitary pulmonary nodules: evaluation of blood flow patterns with dynamic CT. Radiology 1997; 205: 4718.
  • 28
    Barentsz JO,Engelbrecht M,Jager GJ,Witjes JA,de LaRosette J,van Der Sanden BP,Huisman HJ,Heerschap A. Fast dynamic gadolinium-enhanced MR imaging of urinary bladder and prostate cancer. J Magn Reson Imaging 1999; 10: 295304.
  • 29
    Maehara N. Experimental microcomputed tomography study of the 3D microangioarchitecture of tumors. Eur Radiol 2003; 13: 155965.
  • 30
    Grabherr S,Hess A,Karolczak M,Thali MJ,Friess SD,Kalender WA,Dirnhofer R,Djonov V. Angiofil-mediated visualization of the vascular system by microcomputed tomography: a feasibility study. Microsc Res Tech 2008; 71: 5516.
  • 31
    Krneta J,Kroll J,Alves F,Prahst C,Sananbenesi F,Dullin C,Kimmina S,Phillips DJ,Augustin HG. Dissociation of angiogenesis and tumorigenesis in follistatin- and activin-expressing tumors. Cancer Res 2006; 66: 568695.
  • 32
    Wiart M,Corot C,Berthezene Y,Violas X,Canet E. CT pulmonary angiography with a macromolecular contrast medium: a comparative study versus iobitridol in rabbits. Invest Radiol 2001; 36: 54753.
  • 33
    Idee JM,Port M,Robert P,Raynal I,Prigent P,Dencausse A,Le Greneur S,Tichkowsky I,Le Lem G,Bourrinet P,Mugel T,Benderbous S, et al. Preclinical profile of the monodisperse iodinated macromolecular blood pool agent P743. Invest Radiol 2001; 36: 419.
  • 34
    Hanahan D. Heretable formation of pancreatic b-cell tumors in transgenic mice expressing recombinant insulin/simian virus 40 oncogene. Nature 1985; 315: 11522.