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Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects
Article first published online: 19 MAR 2009
DOI: 10.1002/ijc.24441
Copyright © 2009 UICC
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How to Cite
McColgan, P. and Sharma, P. (2009), Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects. Int. J. Cancer, 125: 1473–1478. doi: 10.1002/ijc.24441
Publication History
- Issue published online: 14 JUL 2009
- Article first published online: 19 MAR 2009
- Manuscript Accepted: 3 MAR 2009
- Manuscript Received: 11 DEC 2008
References
- 1,. Biology and biochemistry of proteinases in tumor invasion. Physiol Rev 1993; 73: 161–95.
- 2,,,,. Metalloproteinases: role in breast carcinogenesis, invasion and metastasis. Breast Cancer Res 2000; 2: 252–7.
- 3,. Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 2006; 25: 9–34.
- 4,,. Matrix metalloproteinases in colorectal cancer: is it worth talking about? Cancer Metastasis Rev 2004; 23: 119–35.
- 5,,. Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer. Clin Genet 2008; 73: 197–211.Direct Link:
- 6,,. Serum matrix metalloproteinases -2, -9 and tissue inhibitors of metalloproteinases -1, -2 in lung cancer—TIMP-1 as a prognostic marker. Anticancer Res 2000; 20: 1311–16.
- 7,,,,,,. Clinicopathologic and prognostic significance of matrilysin expression at the invasive front in human colorectal cancers. Int J Cancer 2001; 95: 290–4.Direct Link:
- 8,,,,,. Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94). Cancer Res 1996; 56: 2815–22.
- 9,,,,,. Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties. J Biol Chem 1997; 272: 5007–15.
- 10,,,,,,. Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2. J Clin Invest 1997; 99: 2509–17.
- 11,,,,,,,,,,. Influence of angiogenetic factors and matrix metalloproteinases upon tumour progression in non-small-cell lung cancer. Br J Cancer 2001; 85: 1706–12.
- 12,,,,,. Human macrophage metalloelastase gene expression in colorectal carcinoma and its clinicopathologic significance. Cancer 2001; 91: 1277–83.Direct Link:
- 13,,,,,,,. Overexpression of matrix metalloproteinase-7 (MMP-7) correlates with tumor proliferation, and a poor prognosis in non-small cell lung cancer. Lung Cancer 2007; 58: 384–91.
- 14,,. Matrix metalloproteinases in colorectal cancer: is it worth talking about? Cancer Metastasis Rev 2004; 23: 119–35.
- 15,,. A general estimator for the variance of the Mantel-Haenszel odds ratio. Am J Epidemiol 1986; 124: 719–23.
- 16,. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719–48.
- 17,. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177–88.
- 18. Systematic reviews in health care: systematic reviews of evaluations of diagnostic and screening tests. BMJ 2001; 323: 157–62.
- 19,,,. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 629–34.
- 20,,,,. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility. Cancer Res 2001; 61: 7825–9.
- 21,,,,,,,,,. Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China. Carcinogenesis 2005; 26: 481–6.
- 22,,,,,,. Matrix metalloproteinase-1 promoter polymorphism and lung cancer risk. Cancer Epidemiol Biomarkers Prev 2005; 14: 567–70.
- 23,,,,,,,. Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer. Carcinogenesis 2006; 27: 1024–9.
- 24,,,,,,. Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer. Lung Cancer 2007; 56: 273–80.
- 25,,,,,,. Correlation between a single nucleotide polymorphism in the matrix metalloproteinase-2 promoter and risk of lung cancer. Cancer Res 2002; 62: 6430–3.
- 26,,,,,,,,. Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility. Carcinogenesis 2005; 26: 1117–21.
- 27,,,,,,. Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer. Lung Cancer 2007; 56: 273–80.
- 28,,,,,,,,. Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility. Carcinogenesis 2005; 26: 1117–21.
- 29,,,,,,,. Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer. Carcinogenesis 2006; 27: 1024–9.
- 30,,,,,,. [Correlation of matrix metalloproteinase-3 polymorphism to genetic susceptibility and lymph node metastasis of non-small cell lung cancer]. Ai Zheng 2005; 24: 305–10.
- 31,,,,,,,,,. Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China. Carcinogenesis 2005; 26: 481–6.
- 32,,,,,,. Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer. Lung Cancer 2007; 56: 273–80.
- 33,,,,,,,,. Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility. Carcinogenesis 2005; 26: 1117–21.
- 34,,,,,,,,,. Association of functional polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 genes with colorectal cancer. Int J Cancer 2002; 102: 526–9.Direct Link:
- 35,,,,. No association between the polymorphisms in matrix metalloproteinase-1 and matrix metalloproteinase-3 promoter regions and colorectal cancer in Chinese. Dis Colon Rectum 2006; 49: 1439–44.
- 36,,,,,,. Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness. Clin Cancer Res 2001; 7: 2344–6.
- 37,,. Matrix metalloproteinase (MMP) -1, -2, -3 and -9 promoter polymorphisms in colorectal cancer. Anticancer Res 2006; 26: 791–5.
- 38,,,. Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer. J Gastroenterol Hepatol 2007; 22: 1064–70.Direct Link:
- 39,,,,,. A single nucleotide polymorphism in the matrix metalloproteinase-2 promoter is associated with colorectal cancer. Biochem Biophys Res Commun 2004; 324: 999–1003.
- 40,,,,. [The correlation between polymorphisms of matrix metalloproteinase-2 and -9 genes and colorectal cancer of Chinese patients]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2006; 23: 78–81.
- 41,,,,,,,,,. Association of functional polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 genes with colorectal cancer. Int J Cancer 2002; 102: 526–9.Direct Link:
- 42,,,,,,. Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness. Clin Cancer Res 2001; 7: 2344–6.
- 43,,,. Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer. J Gastroenterol Hepatol 2007; 22: 1064–70.Direct Link:
- 44,,,. Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer. J Gastroenterol Hepatol 2007; 22: 1064–70.Direct Link:
- 45,,,,,,,. Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese. Mol Carcinog 2007; 46: 924–9.Direct Link:
- 46,,,,,,,. Matrix metalloproteinase-9–1562C>T polymorphism may increase the risk of lymphatic metastasis of colorectal cancer. World J Gastroenterol 2007; 13: 4626–9.
- 47,,,,,,,,,,. An association between the matrix metalloproteinase 1 promoter gene polymorphism and lymphnode metastasis in breast cancer. J Exp Clin Cancer Res 2004; 23: 121–5.
- 48,,,,,,,,,. Polymorphisms of the promoter regions of matrix metalloproteinases genes MMP-1 and MMP-9 in breast cancer. Breast Cancer Res Treat 2006; 95: 65–72.
- 49,,,,,,,. Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes. Carcinogenesis 2004; 25: 399–404.
- 50,,,,,,,. Promoter polymorphisms in matrix metalloproteinases and their inhibitors: few associations with breast cancer susceptibility and progression. Breast Cancer Res Treat 2007; 103: 61–9.
- 51,,,,,,,,,,,, et al. Matrix metalloproteinase-2 promoter polymorphism is associated with breast cancer in a Mexican population. Gynecol Obstet Invest 2008; 65: 68–72.
- 52,,,,,. Detection of polymorphisms in the promoters of matrix metalloproteinases 2 and 9 genes in breast cancer in South Brazil: preliminary results. Breast Cancer Res Treat 2007; 102: 123–4.
- 53,,,,,,. A single nucleotide polymorphism in the matrix metalloproteinase-3 promoter enhances breast cancer susceptibility. Clin Cancer Res 2002; 8: 3820–3.
- 54,,,,,,,,. The 5A/6A polymorphism of the matrix metalloproteinase 3 gene promoter and breast cancer. Clin Cancer Res 2004; 10: 3518–20.
- 55,,,,,,,. Promoter polymorphisms in matrix metalloproteinases and their inhibitors: few associations with breast cancer susceptibility and progression. Breast Cancer Res Treat 2007; 103: 61–9.
- 56,,,,,. Detection of polymorphisms in the promoters of matrix metalloproteinases 2 and 9 genes in breast cancer in South Brazil: preliminary results. Breast Cancer Res Treat 2007; 102: 123–4.
- 57,,,,,. Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals. PLoS Med 2007; 4: e131.
- 58,,,. Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. Arch Neurol 2004; 61: 1652–61.
- 59,,,,,. The genetics of primary haemorrhagic stroke. Subarachnoid haemorrhage and ruptured intracranial aneurysms in adults. PLoS ONE 2008; 3: e3691.
- 60,,,,,,,,,. Association of functional polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 genes with colorectal cancer. Int J Cancer 2002; 102: 526–9.Direct Link:
- 61,,,,,,. Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness. Clin Cancer Res 2001; 7: 2344–6.
- 62,,,. Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer. J Gastroenterol Hepatol 2007; 22: 1064–70.Direct Link:
- 63,,. Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 events. Cancer Epidemiol Biomarkers Prev 2007; 16: 2533–47.
- 64,,,,,,,,,,,. Alcohol drinking and colorectal cancer in Japanese: a pooled analysis of results from five cohort studies. Am J Epidemiol 2008; 167: 1397–406.
- 65,,,,. Population-attributable risk for colon cancer in Italy. Nutr Cancer 1999; 33: 196–200.
- 66,,,,,,. Control of confounding of genetic associations in stratified populations. Am J Hum Genet 2003; 72: 1492–504.
- 67,,,,,. Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals. PLoS Med 2007; 4: e131.
- 68,,,. Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. Arch Neurol 2004; 61: 1652–61.

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