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Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid†

  1. Ruth Chu1,
  2. Xiaoyue Zhao1,
  3. Chandi Griffin2,
  4. Richard E. Staub1,
  5. Mark Shoemaker1,
  6. Joan Climent3,
  7. Dale Leitman2,
  8. Isaac Cohen1,
  9. Emma Shtivelman1,
  10. Sylvia Fong1,‡,*

Article first published online: 21 DEC 2009

DOI: 10.1002/ijc.25116

Issue

International Journal of Cancer

International Journal of Cancer

Volume 127, Issue 5, pages 1209–1219, 1 September 2010

Additional Information

How to Cite

Chu, R., Zhao, X., Griffin, C., Staub, R. E., Shoemaker, M., Climent, J., Leitman, D., Cohen, I., Shtivelman, E. and Fong, S. (2010), Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid. Int. J. Cancer, 127: 1209–1219. doi: 10.1002/ijc.25116

Author Information

  1. 1

    Bionovo Inc., Emeryville, CA

  2. 2

    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California at San Francisco, San Francisco, CA

  3. 3

    Cancer Research Institute, University of California at San Francisco, San Francisco, CA

  1. ‡

    Tel.: 510-420-4167, Fax: 510-420-4197

*Bionovo Inc. Emeryville, CA 94608, USA

  1. †

    Conflict of interest: Ruth Chu, Xiaoyue Zhao, Richard E. Staub, Mark Shoemaker, Isaac Cohen, Emma Shtivelman and Sylvia Fong are employees of Bionovo Inc. that supported the work carried out in this article.

Publication History

  1. Issue published online: 25 JUN 2010
  2. Article first published online: 21 DEC 2009
  3. Manuscript Accepted: 26 NOV 2009
  4. Manuscript Received: 13 MAY 2009

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