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Identification of potential pharmacogenomic markers of clinical efficacy of 5-fluorouracil in colorectal cancer

  1. Stefania Nobili1,
  2. Cristina Napoli1,
  3. Ida Landini1,
  4. Maria Morganti1,
  5. Fabio Cianchi2,
  6. Rosa Valanzano3,
  7. Francesco Tonelli3,
  8. Camillo Cortesini2,
  9. Teresita Mazzei1,
  10. Enrico Mini1,†,*

Article first published online: 17 JUN 2010

DOI: 10.1002/ijc.25514

Issue

International Journal of Cancer

International Journal of Cancer

Volume 128, Issue 8, pages 1935–1945, 15 April 2011

Additional Information

How to Cite

Nobili, S., Napoli, C., Landini, I., Morganti, M., Cianchi, F., Valanzano, R., Tonelli, F., Cortesini, C., Mazzei, T. and Mini, E. (2011), Identification of potential pharmacogenomic markers of clinical efficacy of 5-fluorouracil in colorectal cancer. Int. J. Cancer, 128: 1935–1945. doi: 10.1002/ijc.25514

Author Information

  1. 1

    Department of Pharmacology, University of Florence, Florence, Italy

  2. 2

    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy

  3. 3

    Department of Clinical Pathophysiology, University of Florence, Florence, Italy

  1. †

    Tel: +39-055-4271305, Fax: +39-055-4271280

*Department of Pharmacology, University of Florence, viale Pieraccini, 6 - 50139 Firenze, Italy

Publication History

  1. Issue published online: 22 FEB 2011
  2. Article first published online: 17 JUN 2010
  3. Accepted manuscript online: 17 JUN 2010 12:00AM EST
  4. Manuscript Accepted: 26 MAY 2010
  5. Manuscript Received: 28 JAN 2010

Funded by

  • Ministero dell'Istruzione, dell'Università e della Ricerca, Rome (PRIN 2005); Associazione Italiana per la Ricerca sul Cancro
  • Milan;
  • Ente Cassa di Risparmio di Firenze
  • Florence;
  • Gruppo Oncologico Chirurgico Cooperativo Italiano, Florence

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    Ryota Nakanishi, Hiroyuki Kitao, Yoshihiko Fujinaka, Nami Yamashita, Makoto Iimori, Eriko Tokunaga, Natsumi Yamashita, Masaru Morita, Yoshihiro Kakeji, Yoshihiko Maehara, FANCJ Expression Predicts the Response to 5-Fluorouracil-Based Chemotherapy in MLH1-Proficient Colorectal Cancer, Annals of Surgical Oncology, 2012,

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  2. 2
    Francesco Crea, Stefania Nobili, Elisa Paolicchi, Gabriele Perrone, Cristina Napoli, Ida Landini, Romano Danesi, Enrico Mini, Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategies, Drug Resistance Updates, 2011, 14, 6, 280

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    Marina Vignoli, Stefania Nobili, Cristina Napoli, Anna Laura Putignano, Maria Morganti, Laura Papi, Rosa Valanzano, Fabio Cianchi, Francesco Tonelli, Teresita Mazzei, Enrico Mini, Maurizio Genuardi, Thymidylate synthase expression and genotype have no major impact on the clinical outcome of colorectal cancer patients treated with 5-fluorouracil, Pharmacological Research, 2011, 64, 3, 242

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View Full Article with Supporting Information (HTML) Get PDF (450K)