Additional Supporting Information may be found in the online version of this article.

IJC_26057_sm_SuppFig1.tif72KSupporting Information Figure 1. Detection of caspase 3 activation in LBH589 treated cells. Cells were treated with LBH589 (5-100nM) for 48 h and caspase 3 activity was measured as described in the text. Activity of caspase 3 in untreated cells was taken as 100% and that of LBH589-treated cells is expressed as percentage of the basal value. Results are expressed as means ± SD; n = 3. Significance vs untreated cells (0): * P< 0.05; ** P< 0.01; *** P< 0.001.
IJC_26057_sm_SuppFig2.tif607KSupporting Information Figure 2. LBH589 effect on mitotic arrest. Combined phase-contrast and fluorescence micrographs of BHT-101 and CAL-62 cells exposed or not to LBH589 and stained with HOECHST 33258. Multinuclear cells are shown by arrow in presence of 50nM of LBH589.
IJC_26057_sm_SuppTable1.doc35KSupporting Information Table 1.
IJC_26057_sm_SuppTable2.doc28KSupporting Information Table 2.

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.