A prospective study in general practice on breast-cancer risk in postmenopausal women

Authors

  • F. de Waard,

    1. Department of Epidemiology, Institute of Social Medicine, University of Utrecht, Utrecht, The Netherlands
    Search for more papers by this author
    • Formerly staff member of the National Institute of General Practitioners, Utrecht, The Netherlands.

  • E. A. Baanders-Van Halewijn

    1. Department of Epidemiology, Institute of Social Medicine, University of Utrecht, Utrecht, The Netherlands
    Search for more papers by this author

Abstract

A prospective study of breast-cancer risk in postmenopausal women has been carried out with the cooperation of 50 general practitioners. A total of 7,259 women have been followed up for an average period of 5.4 years (maximum 8.1 years); 70 cases of breast cancer occurred. The main finding was a pronounced effect of body weight and height on breast cancer risk; the significance of this in explaining international differences in incidence is stressed. High parity counteracted the risk of high weight regarding breastcancer. Single women did not show a high risk because of their relatively low body weight. The relative risk in women with a previous mastectomy was five-fold.

Ancillary