Nutrition and cancer of the oral cavity and pharynx in north-east italy

Authors

  • Silvia Franceschi,

    Corresponding author
    1. Epidemiology Unit, Aviano Cancer Center, Via Pedemontana Occ, 33081 Aviano (PN), Italy
    2. Hormones, Sexual Factors and Cancer Group–European Organization for Cooperation in Cancer Prevention Studies (ECP), Brussels, Belgium
    • Epidemiology Unit, Aviano Cancer Center, Via Pedemontana Occ., 33081 Aviano (PN), Italy
    Search for more papers by this author
  • Ettore Bidoli,

    1. Epidemiology Unit, Aviano Cancer Center, Via Pedemontana Occ, 33081 Aviano (PN), Italy
    Search for more papers by this author
  • Anna E. Barón,

    1. Epidemiology Unit, Aviano Cancer Center, Via Pedemontana Occ, 33081 Aviano (PN), Italy
    2. Department of Preventive Medicine and Biometrics, University of Colorado, Health Science Center, 4200 E. 9th Ave., 4 B-119, Denver, CO, 80262, USA
    Search for more papers by this author
  • Salvatore Barra,

    1. Epidemiology Unit, Aviano Cancer Center, Via Pedemontana Occ, 33081 Aviano (PN), Italy
    Search for more papers by this author
  • Renato Talamini,

    1. Epidemiology Unit, Aviano Cancer Center, Via Pedemontana Occ, 33081 Aviano (PN), Italy
    Search for more papers by this author
  • Diego Serraino,

    1. Epidemiology Unit, Aviano Cancer Center, Via Pedemontana Occ, 33081 Aviano (PN), Italy
    Search for more papers by this author
  • Carlo La Vecchia

    1. “Mario Negri” Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
    2. Institute of Social and Preventive Medicine, University of Lausanne, 1005 Lausanne, Switzerland
    Search for more papers by this author

Abstract

The relation between dietary indicators and the risk of cancer of the oral cavity and pharynx was investigated in a case-control study conducted in Pordenone province, north-east Italy, on 302 cases (266 males and 36 females) and 699 controls admitted to hospital for acute, non-neoplastic and non-digestive disorders. Positive associations were observed, after allowing for occupation, smoking and drinking habits, with more frequent consumption of pasta or rice, polenta, cheese, eggs and pulses (odds ratios - Ors = 1.6, 2.1, 1.9, 1.9 and 2.0 for highest vs. lowest tertile), whereas reduced ORs emerged in subjects reporting more frequent consumption of carrots, fresh tomatoes and green peppers (ORs = 0.6, 0.5 and 0.5, respectively). Higher frequency of daily meals was also associated with a significantly elevated OR (1.7 for ≥ 4 vs. ≤ 2 meals). The role of various indicator foods must be assessed in the context of the very high levels of alcohol consumption in the study area (≥ 8 alcoholic drinks/day in 2/3 cancer cases).

Ancillary