Survival of breast cancer patients in relation to factors which affect the risk of developing breast cancer

Authors

  • Marianne Ewertz,

    Corresponding author
    1. Danish Cancer Registry, Institute of Cancer Epidemiology, Danish Cancer Society, Rosenvængets Hovedvej 35, Box 839, DK-2100 Copenhagen, Denmark
    • Danish Cancer Registry, Institute of Cancer Epidemiology, Danish Cancer Society, Rosenvængets Hovedvej 35, Box 839, DK-2100 Copenhagen, Denmark
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  • Sonya Gillanders,

    1. Danish Cancer Registry, Institute of Cancer Epidemiology, Danish Cancer Society, Rosenvængets Hovedvej 35, Box 839, DK-2100 Copenhagen, Denmark
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  • Lesley Meyer,

    1. Danish Cancer Registry, Institute of Cancer Epidemiology, Danish Cancer Society, Rosenvængets Hovedvej 35, Box 839, DK-2100 Copenhagen, Denmark
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  • Karin Zedeler

    1. Danish Breast Cancer Co-operative Group, Strandboulevarden 49, DK-2100 Copenhagen, Denmark
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Abstract

In order to evaluate the prognostic significance of risk factors for developing breast cancer, a population-based study was conducted of 2,445 breast cancer patients diagnosed in Denmark, 1983-1984. Data on clinical and pathological characteristics of breast cancer were derived from the Danish Breast Cancer Cooperative Group and data on risk factors from self-administered questionnaire. Among 1,744 patients (71%) with complete information, survival was determined primarily by size of the tumour, skin invasion, number of positive lymph nodes and grade. No significant association was found between survival and reproductive or hormonal risk factors, dietary variables, alcohol consumption and smoking. Low current body weight and weight loss indicated a poor prognosis, independent of the clinical characteristics of the tumour.

Ancillary