Group 9 Transition Metal-Catalyzed C−H Halogenations

Abstract

The high importance of organic halides as synthetic precursors has led to the development of milder and environmentally benign methods for their synthesis. In this regard, transition metal catalyzed C−H activation has emerged as one of the most promising methods for the synthesis of organic halides with high atom economy and excellent stereo- and regio-control. Despite the dominance of palladium and copper catalysts in the field of C−H halogenation reactions, iridium-, rhodium- and cobalt-complexes have also recently been employed as highly efficient catalysts for the formation of carbon-halogen bonds. This review describes the current state of the art in the field of C−H halogenation reactions using group nine transition metal (Co, Rh, Ir) catalysts.