• 1
    Liu, R. Y. and Snider, W. D. ( 2001) Different signaling pathways mediate regenerative versus developmental sensory axon growth. J. Neurosci. 21, RC164.
  • 2
    Peterson, W. M., Wang, Q., Tzekova, R., and Wiegand, S. J. ( 2000) Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia. J. Neurosci. 20, 40814090.
  • 3
    Raptis, L., Arulanandam, R., Geletu, M., and Turkson, J. ( 2011) The R(h)oads to Stat3: Stat3 activation by the Rho GTPases. Exp. Cell Res. 317, 17871795.
  • 4
    Zhao, J. B., Zhang, Y., Li, G. Z., Su, X. F., and Hang, C. H. ( 2011) Activation of JAK2/STAT pathway in cerebral cortex after experimental traumatic brain injury of rats. Neurosci. Lett. 498, 147152.
  • 5
    Bromberg, J. and Darnell, J. E.Jr. ( 2000) The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19, 24682473.
  • 6
    Brockman, J. L., Schroeder, M. D., and Schuler, L. A. ( 2002) PRL activates the cyclin D1 promoter via the Jak2/Stat pathway. Mol. Endocrinol. 16, 774784.
  • 7
    Quintanilla-Martinez, L., Kremer, M., Specht, K., Calzada-Wack, J., and Nathrath, M., et al. ( 2003) Analysis of signal transducer and activator of transcription 3 (Stat 3) pathway in multiple myeloma: Stat 3 activation and cyclin D1 dysregulation are mutually exclusive events. Am. J. Pathol. 162, 14491461.
  • 8
    Simon, A. R., Takahashi, S., Severgnini, M., Fanburg, B. L., and Cochran, B. H. ( 2002) Role of the JAK-STAT pathway in PDGF-stimulated proliferation of human airway smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 282, L1296L1304.
  • 9
    Mao, Y., Li, Z., Lou, C., and Zhang, Y. ( 2011) Expression of phosphorylated Stat5 predicts expression of cyclin D1 and correlates with poor prognosis of colonic adenocarcinoma. Int. J. Colorectal Dis. 26, 2935.
  • 10
    Artegiani, B., Lindemann, D., Calegari, F. ( 2011) Overexpression of cdk4 and cyclin D1 triggers greater expansion of neural stem cells in the adult mouse brain. J. Exp. Med. 208, 937948.
  • 11
    Borowiec, A. S., Hague, F., Gouilleux-Gruart, V., Lassoued, K., and Ouadid-Ahidouch, H. ( 2011) Regulation of IGF-1-dependent cyclin D1 and E expression by hEag1 channels in MCF-7 cells: the critical role of hEag1 channels in G1 phase progression. Biochim. Biophys. Acta. 1813, 723730.
  • 12
    Yadav, A., Kalita, A., Dhillon, S., and Banerjee, K. ( 2005) JAK/STAT3 pathway is involved in survival of neurons in response to insulin-like growth factor and negatively regulated by suppressor of cytokine signaling-3. J. Biol. Chem. 280, 3183031840.
  • 13
    Kenchappa, P., Yadav, A., Singh, G., Nandana, S., and Banerjee, K. ( 2004) Rescue of TNFalpha-inhibited neuronal cells by IGF-1 involves Akt and c-Jun N-terminal kinases. J. Neurosci. Res. 76, 466474.
  • 14
    Gupta, S., Mishra, K., Surolia, A., and Banerjee, K. ( 2011) Suppressor of cytokine signalling-6 promotes neurite outgrowth via JAK2/STAT5-mediated signalling pathway, involving negative feedback inhibition. PLoS One. 6, e26674.
  • 15
    Fujii, H., Nakagawa, Y., Schindler, U., Kawahara, A., Mori, H., et al. ( 1995) Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor 1B chain but is not essential for the proliferative signal transmission. Proc. Natl. Acad. Sci. U.S.A. 92, 54825486.
  • 16
    Dufourny, B., Alblas, J., van Teeffelen, H. A., van Schaik, F. M., and van der Burg, B., et al. ( 1997) Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J. Biol. Chem. 272, 3116331171.
  • 17
    Nakasato, M., Shirakura, Y., Ooga, M., Iwatsuki, M., and Ito, M., et al. ( 2006) Involvement of the STAT5 signaling pathway in the regulation of mouse preimplantation development. Biol. Reprod. 75, 508517.
  • 18
    Xi, S., Gooding, W. E., and Grandis, J. R. ( 2005) In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach: implications for cancer therapy. Oncogene 24, 970979.
  • 19
    Turkson, J. and Jove, R. ( 2000) STAT proteins: novel molecular targets for cancer drug discovery. Oncogene 19, 66136626.
  • 20
    Atwal, J. K., Massie, B., Miller, F.D., and Kaplan, D. R. ( 2000) The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron 27, 265277.
  • 21
    Matsumura, I., Kitamura, T., Wakao, H., Tanaka, H., and Hashimoto, K., et al. ( 1999) Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. Embo J. 18, 13671377.
  • 22
    Leslie, K., Lang, C., Devgan, G., Azare, J., and Berishaj, M., et al. ( 2006). cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Res. 66, 25442552.
  • 23
    Mirza, A. M., Gysin, S., Malek, N., Nakayama, K., and Roberts, J.M., et al. ( 2004) Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT. Mol. Cell Biol. 24, 1086810881.
  • 24
    Bhatt, K.V., Spofford, L. S., Aram, G., McMullen, M., and Pumiglia, K., et al. ( 2005) Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling. Oncogene. 24, 34593471.
  • 25
    Savell, J., Ma, Y., Morrow, K. S., Jove, R., and Olashaw, N., et al. ( 2004) AG490 inhibits G1-S traverse in BALB/c-3T3 cells following either mitogenic stimulation or exogenous expression of E2F-1. Mol. Cancer Ther. 3, 205213.
  • 26
    Murray, P. J. ( 2007) The JAK-STAT signaling pathway: input and output integration. J. Immunol. 178, 26232629.
  • 27
    Gao, B. ( 2005) Cytokines, STATs and liver disease. Cell Mol. Immunol. 2, 92100.