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ejp196-sup-0001-figureS1.pptx1003K

Figure S1. Time course of the expression and phosphorylation of PKCγ and PKCε by NO donors administration. GTN (A) and SNP (B) increased pPKCγ and pPKCε 1, 2 and 4 h after administration, whereas at 6 h the protein levels returned comparable to control values. Administration of calphostin C (C; 0.2 μg per mouse i.c.v.) counteracted the upregulation of pPKCγ and pPKCε. Increased levels of total PKCγ (C) and PKCε (D) was also detected 2 and 4 h after NO donors' administration.

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