The history and trajectory of the Rehabilitation Nursing Foundation (RNF), the research arm of the Association of Rehabilitation Nurses, is presented in this article. From 1988 through 2008, 52 RNF research grants have been awarded to 49 researchers. Since 1995, this research award program has been guided by the Rehabilitation Nursing Research Agenda. Funded studies have varied in focus from pediatrics to geriatrics, to specific chronic conditions, and to administrative and management issues, providing a basis for the development of rehabilitation nursing science. Strategies for successful RNF grant writing are also included in this article.