Assessing carbon-encapsulated iron nanoparticles cytotoxicity in Lewis lung carcinoma cells (pages 380–394)
Ireneusz P. Grudzinski, Michal Bystrzejewski, Monika A. Cywinska, Anita Kosmider, Magdalena Poplawska, Andrzej Cieszanowski, Zbigniew Fijalek, Agnieszka Ostrowska and Andrzej Parzonko
Article first published online: 11 NOV 2013 | DOI: 10.1002/jat.2947
The cytotoxic effect of carbon-encapsulated iron nanoparticles (CEINs) was examined in Lewis lung carcinoma cells. The CEIN samples were synthesized using a carbon arc route, and the as-synthesized CEINs were characterized and examined as raw and purified nanomaterials containing the carbon surface modified with acidic groups. Our results shed new light on the rational design of CEINs, as their geometry, hydrodynamic and, in particular, surface characteristics are important features in selecting CEINs as future magnetic nanomaterials for nanomedicine applications.