Graphene supports in vitro proliferation and osteogenic differentiation of goat adult mesenchymal stem cells: potential for bone tissue engineering (pages 367–374)
Hoda Elkhenany, Lisa Amelse, Andersen Lafont, Shawn Bourdo, Marc Caldwell, Nancy Neilsen, Enkeleda Dervishi, Oshin Derek, Alexandru S. Biris, David Anderson and Madhu Dhar
Article first published online: 12 SEP 2014 | DOI: 10.1002/jat.3024
Current treatments for bone loss injuries involve autologous and allogenic bone grafts, metal alloys, and ceramics. Although these therapies have proved to be useful, they suffer from inherent challenges, hence, an adequate bone replacement therapy has not yet been found. We hypothesize that graphene may be a useful nanoscaffold for mesenchymal stem cells and will promote proliferation and differentiation into bone progenitor cells. In this study we evaluate a combination of graphene and goat mesenchymal stem cells for bone regeneration.