Dynamic microvascular responses with a high speed TiVi imaging system

Authors

  • Jim O'Doherty,

    Corresponding author
    1. Department of Medical Physics, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK
    • Phone: +00 44 1483 406701, Fax: +00 44 1483 406702
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  • Paul M. McNamara,

    1. Biophotonics Research Facility, National Biophotonics and Imaging Platform Ireland NBIPI, Department of Physics, University of Limerick, Ireland
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  • Barry W. Fitzgerald,

    1. Biophotonics Research Facility, National Biophotonics and Imaging Platform Ireland NBIPI, Department of Physics, University of Limerick, Ireland
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  • Martin J. Leahy

    1. Biophotonics Research Facility, National Biophotonics and Imaging Platform Ireland NBIPI, Department of Physics, University of Limerick, Ireland
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Abstract

TiVi technology presents a high resolution, low speed methodology for imaging microcirculation. Recently, the TiVi system was adapted to produce a high speed system capable of analysing dynamic responses from human tissues at a frame rate of 30 frames per second. We present results based on this system by investigating dynamic responses such as arterial pulsations both from a controlled flow model and in vivo tissue sites. We also quantify the effects of sympathetic vasomotion, a biological effect which is evident in many tissue sites, and show that the effects of arterial pulsations and vasomotion on the resulting TiVi time traces are easily determined. (© 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

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