Real-time monitoring of incision profile during laser surgery using shock wave detection

Authors

  • Erwin Bay,

    1. Institute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, 85764 Neuherberg, Germany
    2. Faculty of Medicine, Technical University of Munich, 81675 Munich, Germany
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  • Xosé Luís Deán-Ben,

    1. Institute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, 85764 Neuherberg, Germany
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  • Genny A. Pang,

    1. Institute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, 85764 Neuherberg, Germany
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  • Alexandre Douplik,

    1. Department of Physics, Ryerson University, Toronto, M5B 2K3 Canada
    2. Clinical Photonics Lab (CPL), School of Advanced Optical Technologies (SAOT), Erlangen, Germany
    3. Medical Photonics Engineering Group (MPEG), Chair of Photonics Technologies, Erlangen, Germany
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  • Daniel Razansky

    Corresponding author
    1. Institute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, 85764 Neuherberg, Germany
    2. Faculty of Medicine, Technical University of Munich, 81675 Munich, Germany
    • Phone: +49-89-3187-1587, Fax: +49-89-3187-3063

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Abstract

Lack of sensory feedback during laser surgery prevents surgeons from discerning the exact location of the incision, which increases duration and complexity of the treatment. In this study we demonstrate a new method for monitoring of laser ablation procedures. Real-time tracking of the exact three dimensional (3D) lesion profile is accomplished by detection of shock waves emanating from the ablation spot and subsequent reconstruction of the incision location using time-of-flight data obtained from multiple acoustic detectors. Here, incisions of up to 9 mm in depth, created by pulsed laser ablation of fresh bovine tissue samples, were successfully monitored in real time. It was further observed that, by utilizing as little as 12 detection elements, the incision profile can be characterized with accuracy below 0.5 mm in all three dimensions and in good agreement with histological examinations. The proposed method holds therefore promise for delivering high precision real-time feedback during laser surgeries. (© 2013 WILEY-VCH Verlag GmbH &Co. KGaA, Weinheim)

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