Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS): prospects for a feedback mechanism for surgical laser systems

Authors

  • Rajesh Kanawade,

    Corresponding author
    1. Clinical Photonics Lab, Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
    2. Institute of Photonics Technologies, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91052 Erlangen, Germany
    • Phone: +49 9131 8523242, Fax: +49 9131 8523234

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  • Fanuel Mahari,

    Corresponding author
    1. Clinical Photonics Lab, Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
    2. Institute of Photonics Technologies, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91052 Erlangen, Germany
    • Phone: +49 9131 8523242, Fax: +49 9131 8523234

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  • Florian Klämpfl,

    1. Clinical Photonics Lab, Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
    2. Institute of Photonics Technologies, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91052 Erlangen, Germany
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  • Maximilian Rohde,

    1. Department of Oral and Maxillofacial Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
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  • Christian Knipfer,

    1. Department of Oral and Maxillofacial Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
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  • Katja Tangermann-Gerk,

    1. Bayerisches Laserzentrum GmbH, Erlangen, Germany
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  • Werner Adler,

    1. Chair of Biometry and Epidemiology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany
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  • Michael Schmidt,

    1. Clinical Photonics Lab, Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
    2. Institute of Photonics Technologies, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91052 Erlangen, Germany
    3. Bayerisches Laserzentrum GmbH, Erlangen, Germany
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  • Florian Stelzle

    1. Clinical Photonics Lab, Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
    2. Department of Oral and Maxillofacial Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
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Abstract

The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using ‘Laser Induced Breakdown Spectroscopy’ (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback control mechanism for clinical laser surgery systems during the laser ablation process. Ex-vivo domestic pig tissue samples (muscle, fat, nerve and skin) were used in this experiment. Atomic emission intensity ratios were analyzed to find a characteristic spectral line for each tissue. The results showed characteristic elemental emission intensity ratios for the respective tissues. The spectral lines and intensity ratios of these specific elements varied among the different tissue types. The main goal of this study is to qualitatively and precisely identify different tissue types for tissue specific laser surgery. (© 2013 WILEY-VCH Verlag GmbH &Co. KGaA, Weinheim)

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