• 1
    Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995; 1: 2731.
  • 2
    Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000; 6: 389395.
  • 3
    Beumer GJ, van Blitterswijk CA, Ponec M. Degradative behaviour of polymeric matrices in (sub)dermal and muscle tissue of the rat: a quantitative study. Biomaterials 1994; 15: 551559.
  • 4
    Beumer GJ, van Blitterswijk CA, Bakker D, Ponec M. A new biodegradable matrix as part of a cell seeded skin substitute for the treatment of deep skin defects: a physico-chemical characterisation. Clin Mater 1993; 14: 2127.
  • 5
    Van Dorp AG, Verhoeven MC, Koerten HK, Van Der Nat-Van Der Meij TH, Van Blitterswijk CA, Ponec M. Dermal regeneration in full-thickness wounds in Yucatan miniature pigs using a biodegradable copolymer. Wound Repair Regen 1998; 6: 55668.
  • 6
    Xiao YRJ, van Blitterswijk CA. Static and dynamic fibroblast seeding and cultivation in porous PEO/PBT scaffolds. J Mater Sci Mater Med 1999; 10: 773777.
  • 7
    Radder AM, Leenders H, van Blitterswijk CA. Application of porous PEO/PBT copolymers for bone replacement. J Biomed Mater Res 1996; 30: 34151.
  • 8
    Bulstra SK, Geesink RG, Bakker D, Bulstra TH, Bouwmeester SJ, van der Linden AJ. Femoral canal occlusion in total hip replacement using a resorbable and flexible cement restrictor. J Bone Joint Surg Br 1996; 78: 892898.
  • 9
    van Loon JALH, Goedemoed JH, van Blitterswswijk CA. Tissue reaction during long term implantation in relation to degradation. A study of range of PEO/PBT copolymers. 20th Annual Meeting of the Society of Biomaterials 1994. p 370.
  • 10
    Wake MC, Patrick CW Jr, Mikos AG. Pore morphology effects on the fibrovascular tissue growth in porous polymer substrates. Cell Transplant 1994; 3: 339343.
  • 11
    Endrich B, Asaishi K, Gotz A, Messmer K: Technical report—a new chamber technique for microvascular studies in unanesthetized hamsters. Res Exp Med (Berlin) 1980; 177: 125134.
  • 12
    Harris AG, Steinbauer M, Leiderer R, Messmer K. Role of leukocyte plugging and edema in skeletal muscle ischemia–reperfusion injury. Am J Physiol 1997; 273: H989H996.
  • 13
    Langer S, Abels C, Botzlar A, Pahernik S, Rick K, Szeimies RM, Goetz AE. Active and higher intracellular uptake of 5-aminolevulinic acid in tumors may be inhibited by glycine. J Invest Dermatol 1999; 112: 723728.
  • 14
    Lehr HA, Leunig M, Menger MD, Nolte D, Messmer K. Dorsal skinfold chamber technique for intravital microscopy in nude mice. Am J Pathol 1993; 143: 10551062.
  • 15
    Menger MD, Hammersen F, Walter P, Messmer K. Neovascularization of prosthetic vascular grafts. Quantitative analysis of angiogenesis and microhemodynamics by means of intravital microscopy. Thorac Cardiovasc Surg 1990; 38: 139145.
  • 16
    Sakai H, Hara H, Tsai AG, Tsuchida E, Intaglietta M. Constriction of resistance arteries determines l-NAME–induced hypertension in a conscious hamster model. Microvasc Res 2000; 60: 2127.
  • 17
    Langer S, Sinitsina I, Biberthaler P, Krombach F, Messmer K. Revascularization of transplanted adipose tissue: a study in the dorsal skinfold chamber of hamsters. Ann Plast Surg 2002; 48: 5359.
  • 18
    Menger MD, Hammersen F, Messmer K. In vivo assessment of neovascularization and incorporation of prosthetic vascular biografts. Thorac Cardiovasc Surg 1992; 40: 1925.
  • 19
    Deodato B, Arsic N, Zentilin L, Galeano M, Santoro D, Torre V, Altavilla D, Valdembri D, Bussolino F, Squadrito F, Giacca M. Recombinant AAV vector encoding human VEGF165 enhances wound healing. Gene Ther 2002; –9: 777785.
  • 20
    van Dorp AG, Verhoeven MC, Koerten HK, van Blitterswijk CA, Ponec M. Bilayered biodegradable poly(ethylene glycol)/poly(butylene terephthalate) copolymer (Polyactive) as substrate for human fibroblasts and keratinocytes. J Biomed Mater Res 1999; 47: 292300.
  • 21
    Klyscz T, Jünger M, Jung F, Zeintl H: [Cap image—a new kind of computer-assisted video image analysis system for dynamic capillary microscopy.] Biomed Tech (Berlin) 1997; 42: 168175.
  • 22
    Harris AG, Leiderer R, Peer F, Messmer K. Skeletal muscle microvascular and tissue injury after varying durations of ischemia. Am J Physiol 1996; 271: H2388H2398.
  • 23
    Langer S, Born F, Harris AG, Hatz R, Biberthaler P, Messmer K. OPS imaging versus intravital fluorescent microscopy for microvascular studies in wounds. Ann Plast Surg 2002; 48: 646653.
  • 24
    Nolte D, Zeintl H, Steinbauer M, Pickelmann S, Messmer K. Functional capillary density: an indicator of tissue perfusion? Int J Microcirc Clin Exp 1995; 15: 244249.
  • 25
    Langer S, Biberthaler P, Harris AG, Steinau HU, Messmer K. In vivo monitoring of microvessels in skin flaps: introduction of a novel technique. Microsurgery 2001; 21: 317324.
  • 26
    Menger MD, Pelikan S, Steiner D, Messmer K. Microvascular ischemia–reperfusion injury in striated muscle: significance of “reflow paradox.” Am J Physiol 1992; 263: H1901H1906.
  • 27
    Lee H, Cusick RA, Browne F, Ho Kim T, Ma PX, Utsunomiya H, Langer R, Vacanti JP. Local delivery of basic fibroblast growth factor increases both angiogenesis and engraftment of hepatocytes in tissue-engineered polymer devices. Transplantation 2002; 73: 15891593.
  • 28
    Soker S, Machado M, Atala A. Systems for therapeutic angiogenesis in tissue engineering. World J Urol 2000; 18: 1018.
  • 29
    Collier JH, Camp JP, Hudson TW, Schmidt CE. Synthesis and characterization of polypyrrole–hyaluronic acid composite biomaterials for tissue engineering applications. J Biomed Mater Res 2000;– 50: 574584.
  • 30
    Pieper JS, Hafmans T, Van Wachem PB, Van Luyn MJ, Brouwer LA, Veerkamp JH, Van Kuppevelt TH. Loading of collagen–heparan sulfate matrices with bFGF promotes angiogenesis and tissue generation in rats. J Biomed Mater Res 2002; 62: 185194.
  • 31
    Brey EM, King TW, Johnston C, McIntire LV, Reece GP, Patrick CW Jr. A technique for quantitative three-dimensional analysis of microvascular structure. Microvasc Res 2002; 63: 279294.
  • 32
    Jamell GA, Hollsten DA, Hawes MJ, Griffin DJ, Klingensmith WC, White WL, Spirnak J. Magnetic resonance imaging versus bone scan for assessment of vascularization of the hydroxyapatite orbital implant. Ophthal Plast Reconstr Surg 1996; 12: 127130.
  • 33
    Yang CF, Yasukawa T, Kimura H, Miyamoto H, Honda Y, Tabata Y, Ikada Y, Ogura Y. Experimental corneal neovascularization by basic fibroblast growth factor incorporated into gelatin hydrogel. Ophthalmic Res 2000; 32: 1924.
  • 34
    Nolte D, Menger MD, Messmer K. Microcirculatory models of ischaemia–reperfusion in skin and striated muscle. Int J Microcirc Clin Exp 1995; 15(Suppl 1): 916.
  • 35
    Menger MD, Vajkoczy P, Beger C, Messmer K. Orientation of microvascular blood flow in pancreatic islet isografts. J Clin Invest 1994; 93: 22802285.
  • 36
    Beumer GJ, van Blitterswijk CA, Bakker D, Ponec M. A new biodegradable matrix as part of a cell seeded skin substitute for the treatment of deep skin defects: a physico-chemical characterisation. Clin Mater 1993; 14: 2127.
  • 37
    Papadaki M, Mahmood T, Gupta P, Claase MB, Grijpma DW, Riesle J, van Blitterswijk CA, Langer R. The different behaviors of skeletal muscle cells and chondrocytes on PEGT/PBT block copolymers are related to the surface properties of the substrate. J Biomed Mater Res 2001; 54: 4758.
  • 38
    Nor JE, Peters MC, Christensen JB, Sutorik MM, Linn S, Khan MK, Addison CL, Mooney DJ, Polverini PJ. Engineering and characterization of functional human microvessels in immunodeficient mice. Lab Invest 2001; 81: 453463.