Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique

  1. Markus Lindner1,†,*,
  2. Simon Hoeges2,†,
  3. Wilhelm Meiners2,
  4. Konrad Wissenbach2,
  5. Ralf Smeets3,
  6. Rainer Telle4,
  7. Reinhart Poprawe5,
  8. Horst Fischer1

Article first published online: 14 APR 2011

DOI: 10.1002/jbm.a.33058

Issue

Journal of Biomedical Materials Research Part A

Journal of Biomedical Materials Research Part A

Volume 97A, Issue 4, pages 466–471, 15 June 2011

Additional Information

How to Cite

Lindner, M., Hoeges, S., Meiners, W., Wissenbach, K., Smeets, R., Telle, R., Poprawe, R. and Fischer, H. (2011), Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique. Journal of Biomedical Materials Research Part A, 97A: 466–471. doi: 10.1002/jbm.a.33058

Author Information

  1. 1

    Department of Dental Materials and Biomaterials Research, University Hospital RWTH Aachen, Germany

  2. 2

    Fraunhofer Institute for Laser Technology ILT, Aachen, Germany

  3. 3

    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Germany

  4. 4

    Institute for Mineral Engineering (GHI), RWTH Aachen University, Germany

  5. 5

    Chair for Laser Technology (LLT), RWTH Aachen University, Germany

  1. †

    These authors contributed equally to this work.

*Department of Dental Materials and Biomaterials Research University Hospital RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany

Publication History

  1. Issue published online: 4 MAY 2011
  2. Article first published online: 14 APR 2011
  3. Manuscript Accepted: 28 SEP 2010
  4. Manuscript Revised: 13 AUG 2010
  5. Manuscript Received: 18 DEC 2009

Funded by

  • BMWi (German Ministry of Economics and Technology). Grant Number: AZ 16IN0443

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Keywords:

  • selective laser melting;
  • calcium phosphate;
  • polylactide;
  • bioceramics;
  • rapid manufacturing

Abstract

The additive manufacturing technique selective laser melting (SLM) has been successfully proved to be suitable for applications in implant manufacturing. SLM is well known for metal parts and offers direct manufacturing of three-dimensional (3D) parts with high bulk density on the base of individual 3D data, including computer tomography models of anatomical structures. Furthermore, an interconnecting porous structure with defined and reproducible pore size can be integrated during the design of the 3D virtual model of the implant. The objective of this study was to develop the SLM processes for a biodegradable composite material made of β-tricalcium phosphate (β-TCP) and poly(D, L)-lactide (PDLLA). The development of a powder composite material (β-TCP/PDLLA) suitable for the SLM process was successfully performed. The microstructure of the manufactured samples exhibit a homogeneous arrangement of ceramic and polymer. The four-point bending strength was up to 23 MPa. The X-ray diffraction (XRD) analysis of the samples confirmed β-TCP as the only present crystalline phase and the gel permeations chromatography (GPC) analysis documented a degradation of the polymer caused by the laser process less than conventional manufacturing processes. We conclude that SLM presents a new possibility to manufacture individual biodegradable implants made of β-TCP/PDLLA. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A:, 2011.

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