Development of silver nanoparticle loaded antibacterial polymer mesh using plasma polymerization process

Authors

  • Virendra Kumar,

    Corresponding author
    1. Laboratoire de Génie des Procédés Plasmas et Traitement de Surface, Université Pierre et Marie Curie, ENSCP- Chimie Paris Tech, 11 rue Pierre et Marie Curie, 75231 Paris cedex 05, France
    2. Radiation Technology Development Division, BARC, Trombay, Mumbai 400085, India
    • Laboratoire de Génie des Procédés Plasmas et Traitement de Surface, Université Pierre et Marie Curie, ENSCP- Chimie Paris Tech, 11 rue Pierre et Marie Curie, 75231 Paris cedex 05, France
    Search for more papers by this author
  • Claude Jolivalt,

    1. Laboratoire Charles Friedel (LCF), Chimie Paris Tech, CNRS UMR 7223, 11 rue Pierre et Marie Curie, 75231 Paris cedex 05, France
    Search for more papers by this author
  • Jerome Pulpytel,

    1. Laboratoire de Génie des Procédés Plasmas et Traitement de Surface, Université Pierre et Marie Curie, ENSCP- Chimie Paris Tech, 11 rue Pierre et Marie Curie, 75231 Paris cedex 05, France
    Search for more papers by this author
  • Reza Jafari,

    1. Département des sciences appliquées, Université du Québec à Chicoutimi, 555, boulevard de l'Université, Chicoutimi, Québec, Canada G7H 2B1
    Search for more papers by this author
  • Farzaneh Arefi-Khonsari

    Corresponding author
    1. Laboratoire de Génie des Procédés Plasmas et Traitement de Surface, Université Pierre et Marie Curie, ENSCP- Chimie Paris Tech, 11 rue Pierre et Marie Curie, 75231 Paris cedex 05, France
    • Laboratoire de Génie des Procédés Plasmas et Traitement de Surface, Université Pierre et Marie Curie, ENSCP- Chimie Paris Tech, 11 rue Pierre et Marie Curie, 75231 Paris cedex 05, France
    Search for more papers by this author

  • How to cite this article: Kumar V, Jolivalt C, Pulpytel J, Jafari R, Arefi-Khonsari F. 2013. Development of silver nanoparticle loaded antibacterial polymer mesh using plasma polymerization process. J Biomed Mater Res Part A 2013:101A:1121–1132.

Abstract

Plasma polymerized polyacrylic acid (PPAA) was deposited on a polymer substrate, namely polyethylene terephthalate (PET) mesh, for entrapment of silver nanoparticle (Ag-NP) in order to achieve antibacterial property to the material. Carboxylic groups of PPAA act as anchor as well as capping and stabilizing agents for Ag-NPs synthesized by chemical reduction method using NaBH4 as a reducing agent. Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy (XPS), and water contact angle analysis were used to characterize the PPAA coatings. The Ag-NPs loaded polymer samples were characterized by UV–visible spectroscopy, field emission scanning electron microscopy, energy dispersive X-ray, and XPS techniques. XPS analysis showed ∼1.0 at.% loading of Ag-NPs on to the PPAA-PET-mesh, which was composed of 79% zero-valent (Ag°) and 21% oxidized nano-Ag (Ag+). The plasma processed PET meshes samples were tested for antibacterial activity against two bacterial strains, namely Staphylococcus aureus (Gram positive) and Escherichia coli (Gram negative). Qualitative and quantitative tests showed that silver containing PPAA-PET meshes exhibit excellent antibacterial property against the tested bacteria with percent reduction of bacterial concentration >99%, compared to the untreated PET mesh. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2013.

Ancillary