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Keywords:

  • polymer-derived ceramics;
  • bioglasses;
  • glass-ceramics;
  • porous scaffolds;
  • bioactivity

Abstract

Highly porous scaffolds with composition similar to those of 45S5 and 58S bioglasses were successfully produced by an innovative processing method based on preceramic polymers containing micro- and nano-sized fillers. Silica from the decomposition of the silicone resins reacted with the oxides deriving from the fillers, yielding glass ceramic components after heating at 1000°C. Despite the limited mechanical strength, the obtained samples possessed suitable porous architecture and promising biocompatibility and bioactivity characteristics, as testified by preliminary in vitro tests. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 102A: 2502–2510, 2014.