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Current status of prosthetic bypass grafts: A review

Authors

  • Ruben Y. Kannan,

    1. Biomaterials & Tissue Engineering Centre, University Department of Surgery, Royal Free and University College Medical School, University College London, London, United Kingdom
    2. Department of Plastic Surgery, Royal Free Hospital Hampstead NHS Trust, London, United Kingdom
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  • Henryk J. Salacinski,

    1. Biomaterials & Tissue Engineering Centre, University Department of Surgery, Royal Free and University College Medical School, University College London, London, United Kingdom
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  • Peter E. Butler,

    1. Department of Plastic Surgery, Royal Free Hospital Hampstead NHS Trust, London, United Kingdom
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  • George Hamilton,

    1. Vascular Unit, Department of Surgery, Royal Free Hospital Hampstead NHS Trust, London, United Kingdom
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  • Alexander M. Seifalian

    Corresponding author
    1. Biomaterials & Tissue Engineering Centre, University Department of Surgery, Royal Free and University College Medical School, University College London, London, United Kingdom
    • Biomaterials & Tissue Engineering Centre, University Department of Surgery, Royal Free and University College Medical School, University College London, London, United Kingdom
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Abstract

Polymers such as Dacron® and polytetrafluoroethylene (PTFE) have been used in high flow states with relative success but with limited application at lower flow states. Newer polymers with greater compliance, biomimicry, and ability to evolve into hybrid prostheses, suitable as smaller vessels, are now being introduced. In view of the advances in tissue engineering, this makes possible the creation of an ideal off-the-shelf bypass graft. We present a broad overview of the current state of prosthetic bypass grafts. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2005

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