How to cite this article: Krucinska I, Komisarczyk A, Paluch D, Szymonowicz M, Zywicka B, Pielka S. 2012. The impact of the dibutyrylchitin molar mass on the bioactive properties of dressings used to treat soft tissue wounds. J Biomed Mater Res Part B 2012:100B:11-22.
The impact of the dibutyrylchitin molar mass on the bioactive properties of dressings used to treat soft tissue wounds†
Article first published online: 24 NOV 2011
Copyright © 2011 Wiley Periodicals, Inc.
Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume 100B, Issue 1, pages 11–22, January 2012
How to Cite
Krucinska, I., Komisarczyk, A., Paluch, D., Szymonowicz, M., Zywicka, B. and Pielka, S. (2012), The impact of the dibutyrylchitin molar mass on the bioactive properties of dressings used to treat soft tissue wounds. J. Biomed. Mater. Res., 100B: 11–22. doi: 10.1002/jbm.b.31895
- Issue published online: 6 DEC 2011
- Article first published online: 24 NOV 2011
- Manuscript Accepted: 9 MAR 2011
- Manuscript Revised: 7 FEB 2011
- Manuscript Received: 17 AUG 2009
- The auspices of program AM no. 1063, financed by the Medical Academy of Wroclaw, Poland
- Research Project no. 3 T08E 030 30 financed by the Ministry of Science and Higher Education, Poland
- bioactive material;
- biocompatibility/soft tissue;
- blood-material interaction;
- wound dressings
In this work, we describe a novel technique for producing biocompatible medical products with bioactive properties from the biodegradable polymer dibutyrylchitin (DBC). Materials produced by blowing out polymer solutions have excellent hemostaic properties and are easy to handle during surgery. Biocompatibility studies, encompassing hemostasis and the evaluation of post-implantation reactions, indicate that the biological properties of DBC depend on the molecular mass of the polymer. Lower molecular mass polymers are preferable for use in implanted wound dressings. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.