How to cite this article: Zhao Q, Wang S, Kong M, Geng W, Li RKY, Song C, Kong D. 2012. Phase morphology, physical properties, and biodegradation behavior of novel PLA/PHBHHx blends. J Biomed Mater Res Part B 2012:100B:23-31.
Phase morphology, physical properties, and biodegradation behavior of novel PLA/PHBHHx blends†
Article first published online: 26 SEP 2011
Copyright © 2011 Wiley Periodicals, Inc.
Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume 100B, Issue 1, pages 23–31, January 2012
How to Cite
Zhao, Q., Wang, S., Kong, M., Geng, W., Li, R. K.Y., Song, C. and Kong, D. (2012), Phase morphology, physical properties, and biodegradation behavior of novel PLA/PHBHHx blends. J. Biomed. Mater. Res., 100B: 23–31. doi: 10.1002/jbm.b.31915
- Issue published online: 6 DEC 2011
- Article first published online: 26 SEP 2011
- Manuscript Accepted: 16 JUN 2011
- Manuscript Revised: 12 JUN 2011
- Manuscript Received: 21 APR 2011
- National Natural Science Foundation of China. Grant Numbers: 50830104, 51073081, 81000680
- Tianjin Committee of Science and Technology, PR China (Key Projects). Grant Numbers: 09JCZDJC18400, 09ZCKFSH00800).
- phase behavior;
- poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx);
- polylactic acid (PLA)
In this study, two biodegradable polyesters [i.e., polylactic acid (PLA) and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx)] with complementarity in terms of mechanical performance have been combined, and a series of blends with a broad range of compositions has been prepared by thermal compounding. The evolution of phase morphologies with the variation of compositions has been characterized by using Fourier transform infrared spectroscopic imaging together with scanning electron microscope analyses. Thermal, mechanical, and biodegradation properties of the PLA/PHBHHx blends were systematically investigated. Mechanical properties were further analyzed by using theoretical models and correlated with the results of the morphology/structure and compatibility of the blends. Results indicate that PLA/PHBHHx blends are immiscible but can be compatible to some extent at certain compositions (e.g., PLA/PHBHHx (w/w) = 80/20 and 20/80). The physical properties of the blend could be fine tuned by adjusting the blend composition. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.