How to cite this article: Choi J, Kung HJ, Macias CE, Muratoglu OK. 2012. Highly lubricious poly(vinyl alcohol)-poly(acrylic acid) hydrogels. J Biomed Mater Res Part B 2012:100B:524–532.
Highly lubricious poly(vinyl alcohol)–poly(acrylic acid) hydrogels†
Article first published online: 28 NOV 2011
Copyright © 2011 Wiley Periodicals, Inc.
Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume 100B, Issue 2, pages 524–532, February 2012
How to Cite
Choi, J., Kung, H. J., Macias, C. E. and Muratoglu, O. K. (2012), Highly lubricious poly(vinyl alcohol)–poly(acrylic acid) hydrogels. J. Biomed. Mater. Res., 100B: 524–532. doi: 10.1002/jbm.b.31980
- Issue published online: 4 JAN 2012
- Article first published online: 28 NOV 2011
- Manuscript Received: 16 DEC 2011
- Manuscript Accepted: 12 JUL 2011
- Manuscript Revised: 5 APR 2011
- Zimmer Inc., Departmental funds
- poly(vinyl alcohol);
- poly(acrylic acid);
- water content;
Poly(vinyl alcohol) (PVA) hydrogels have desirable characteristics for use as artificial cartilage, such as biocompatibility, high water content, and surface lubricity. However, PVA hydrogels are not strong enough to withstand the demanding load-bearing environment in human joints. Thermal annealing can greatly improve compressive strength, but it also causes substantial loss in water content and lubricity. We demonstrated that incorporating anionic moieties of poly(acrylic acid) improves surface lubricity, whereas adding poly(ethylene-glycol) prevents pore collapse during thermal annealing, yielding a tough hydrogel with high lubricity. We also found a “super-lubricous” response from the gels when they were annealed in air versus argon gas. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 100B: 524–532, 2012.