How to cite this article: Wang M, Kornfield JA. 2012. Measuring shear strength of soft-tissue adhesives. J Biomed Mater Res Part B 2012:100B:618–623.
Measuring shear strength of soft-tissue adhesives†
Article first published online: 10 FEB 2012
Copyright © 2012 Wiley Periodicals, Inc.
Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume 100B, Issue 3, pages 618–623, April 2012
How to Cite
Wang, M. and Kornfield, J. A. (2012), Measuring shear strength of soft-tissue adhesives. J. Biomed. Mater. Res., 100B: 618–623. doi: 10.1002/jbm.b.31981
- Issue published online: 2 MAR 2012
- Article first published online: 10 FEB 2012
- Manuscript Accepted: 2 JUN 2011
- Manuscript Revised: 5 APR 2011
- Manuscript Received: 17 OCT 2010
- The Jacobs Institute for Molecular Engineering for Medicine, Caltech
- tissue adhesion;
A method for evaluating strength of adhesives for hydrogels and soft tissues is presented. Quantitative measurements of shear strength for applications in tissue engineering and biomedicine are performed in torsion using a rheometer. Small, disk shaped specimens of soft biological tissues and/or hydrogels (8 mm diameter, 1–2 mm thick) are mounted onto rheometer tools and then bonded together using the adhesive to be tested. The torsional loading geometry imposes simple shear without deforming the planar adhesive bond, in contrast to the lap-shear test. It retains the advantages of the napkin ring test while reducing artifacts due to cutting and handling soft specimens. The method is demonstrated by measuring the shear strength of two types of biomedical adhesives (cyanoacrylate and polyethylene glycol-based) between model hydrogels (gelatin) and tissues (corneal stroma and skin). © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.