How to cite this article: Yamauchi K, Takahashi T, Tanaka K, Nogami S, Kaneuji T, Kanetaka H, Miyazaki T, Lethaus B, Kessler P. 2013. Self-activated mesh device using shape memory alloy for periosteal expansion osteogenesis. J Biomed Mater Res Part B 2013:101B:736–742.
Self-activated mesh device using shape memory alloy for periosteal expansion osteogenesis†
Article first published online: 29 JAN 2013
Copyright © 2013 Wiley Periodicals, Inc.
Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume 101B, Issue 5, pages 736–742, July 2013
How to Cite
Yamauchi, K., Takahashi, T., Tanaka, K., Nogami, S., Kaneuji, T., Kanetaka, H., Miyazaki, T., Lethaus, B. and Kessler, P. (2013), Self-activated mesh device using shape memory alloy for periosteal expansion osteogenesis. J. Biomed. Mater. Res., 101B: 736–742. doi: 10.1002/jbm.b.32876
- Issue published online: 8 JUN 2013
- Article first published online: 29 JAN 2013
- Manuscript Accepted: 29 OCT 2012
- Manuscript Revised: 27 SEP 2012
- Manuscript Received: 2 APR 2012
- animal model;
- bone graft;
The present study evaluated the use of this self-activated shape memory alloy (SMA) device, with a focus on its effects in the region under the periosteum. Twelve Japanese white rabbits were used in this study. The device was inserted under the periosteum at the forehead. In the experimental group, the device was pushed, bent, and attached to the bone surface and fixed with a titanium screw. In control group, the device was only inserted under the periosteum. After 14 days, the screw was removed and the mesh was activated in the experimental group. Rabbits were sacrificed 5 and 8 weeks after the operation and newly formed bone was histologically and radiographically evaluated. The quantitative data by the area and the occupation of newly formed bone indicated that the experimental group had a higher volume of new bone than the control group at each consolidation period. Histologically, some newly formed bone was observed and most of the subperiosteal space underneath the device was filled with fibrous tissue, and a thin layer of immature bone was observed in the control group. In the experimental group, multiple dome-shaped bones, outlined by thin and scattered trabeculae, were clearly observed under the SMA mesh device. The use of self-activated devices for the periosteal expansion technique may make it possible to avoid donor site morbidity, trans-skin activation rods, any bone-cutting procedure, and the following intermittent activation procedure. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2013.