Original Research Report
Better primary stability with porous titanium particles than with bone particles in cemented impaction grafting: An in vitro study in synthetic acetabula
Article first published online: 7 MAY 2013
Copyright © 2013 Wiley Periodicals, Inc., a Wiley Company
Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume 101, Issue 7, pages 1243–1250, October 2013
How to Cite
How to cite this article: 2013. Better primary stability with porous titanium particles than with bone particles in cemented impaction grafting: An in vitro study in synthetic acetabula.J Biomed Mater Res Part B 2013:101B:1243–1250., , , , .
- Issue published online: 11 SEP 2013
- Article first published online: 7 MAY 2013
- Manuscript Accepted: 30 JAN 2013
- Manuscript Revised: 27 NOV 2012
- Manuscript Received: 22 APR 2012
- Fondel Medical B.V., Rotterdam, The Netherlands
- in vitro;
Impaction bone grafting creates new bone stock after hip joint replacement. Utilizing a synthetic bone substitute instead of bone might increase primary stability and is not associated with graft shortage and pathogen transmission. This study compares the initial stability of a graft layer of porous titanium particles (TiP), cancellous bone particles, and a 1:2 bone-titanium mix in synthetic cemented acetabular reconstructions. Displacement was measured by radiostereometric analysis after cyclic loading (1 Hz, maximum stress 2.5 MPa). Shear stress resistance was quantified by a lever out test of the cup. Cement penetration was quantified from cross-sections.
Titanium reconstructions showed less residual displacement (0.13 ± 0.13 mm) than pure bone particle reconstructions (0.57 ± 0.18 mm) (p < 0.01). Titanium reconstructions were also more resistant to shear stress (p < 0.001). The bone-titanium mix showed intermediate results. Cement penetrated deeper into the bone particle graft layers (4.8 ± 0.7) than into the titanium graft layers (3.8 ± 0.5 mm) (p < 0.02).
Cemented acetabular revision reconstructions with porous TiP show better initial stability despite less cement penetration than bone particle reconstructions. Realistic preclinical in vivo testing should explore the hypothesis that porous TiP offer a safe alternative to the current gold standard of bone grafts. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 101B: 1243–1250, 2013.