The need for stent–lesion matching to optimize outcomes of intracoronary stent implantation
Article first published online: 17 MAY 2013
Copyright © 2013 Wiley Periodicals, Inc.
Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume 101, Issue 8, pages 1560–1570, November 2013
How to Cite
How to cite this article: 2013. The need for stent–lesion matching to optimize outcomes of intracoronary stent implantation. J Biomed Mater Res Part B 2013:101B:1560–1570., , , .
- Issue published online: 22 OCT 2013
- Article first published online: 17 MAY 2013
- Manuscript Accepted: 17 FEB 2013
- Manuscript Revised: 1 OCT 2012
- Manuscript Received: 9 DEC 2011
- intracoronary stenting;
- coronary artery lesions;
- lesion matching
Intracoronary stents have markedly improved the outcomes of catheter-based coronary interventions. Intracoronary stent implantation rates of over 90% during coronary angioplasty are common. Stent implantations are associated with a small but statistically significant number of adverse outcomes including restenosis, thrombosis, strut malapposition, incomplete strut endothelialization, and various types of stenting failure. Better matching of biomechanical properties of stents and lesions could further improve the clinical outcome of intracoronary stenting. Thus, in this article, we assess the need for advanced intracoronary stent–lesion matching. We reviewed the data on biomechanics of coronary stents and lesions to develop knowledge-based rationale for optimum intracoronary stent selection. The available technical information on marketed intracoronary stents and the current understanding of the biomechanical properties of coronary lesions at rest and under stress are limited, preventing the development of knowledge-based rationale for optimum intracoronary stent selection at present. Development of knowledge-based selection of intracoronary stents requires standardization of mechanical stent testing, communication of the nonproprietary technical data on stents by the industry and dedicated research into procedural stent–lesion interactions. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 101B: 1560–1570, 2013.