The first two authors contributed equally to this work.
Sclerostin Regulates Release of Bone Mineral by Osteocytes by Induction of Carbonic Anhydrase 2
Article first published online: 19 NOV 2013
© 2013 American Society for Bone and Mineral Research
Journal of Bone and Mineral Research
Volume 28, Issue 12, pages 2436–2448, December 2013
How to Cite
Kogawa, M., Wijenayaka, A. R., Ormsby, R. T., Thomas, G. P., Anderson, P. H., Bonewald, L. F., Findlay, D. M. and Atkins, G. J. (2013), Sclerostin Regulates Release of Bone Mineral by Osteocytes by Induction of Carbonic Anhydrase 2. J Bone Miner Res, 28: 2436–2448. doi: 10.1002/jbmr.2003
For a Commentary on this article, please see Arnett (J Bone Miner Res. 2013;28:2433–2435. DOI: 10.1002/jbmr.2119).
- Issue published online: 19 NOV 2013
- Article first published online: 19 NOV 2013
- Accepted manuscript online: 5 JUN 2013 05:36AM EST
- Manuscript Accepted: 17 MAY 2013
- Manuscript Revised: 6 MAY 2013
- Manuscript Received: 4 OCT 2012
- National Health and Medical Research Council of Australia (NHMRC). Grant Numbers: 565372, 1004871
Additional Supporting Information may be found in the online version of this article.
|jbmr2003-sm-0001-SuppFig-S1.pdf||43K||Fig. S1. Extent and specificity of Lrp knockdown by siRNA. MLO-Y4 cells were transfected with optimised doses of siRNA constructs specific for mouse Lrp4, Lrp5 and Lrp6 mRNA or a corresponding negative control siRNAs (siNEG and siEGFP). After 48 hours, total RNA was prepared and RT-PCR performed for each Lrp as described in Materials and Methods. The percentage knockdown for each siRNA is indicated. Significance is represented by *p < 0.01.|
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