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Journal of Bone and Mineral Research

Copyright © 2013 American Society for Bone and Mineral Research

Cover image for Vol. 27 Issue 3

March 2012

Volume 27, Issue 3

Pages 499–737

  1. Perspective

    1. Top of page
    2. Perspective
    3. Commentary
    4. Original Articles
    5. Clinical Vignette
    6. Short Reports
    7. Case Report
    1. You have free access to this content
      Osteocyte RANKL: New insights into the control of bone remodeling (pages 499–505)

      Jinhu Xiong and Charles A O'Brien

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1547

  2. Commentary

    1. Top of page
    2. Perspective
    3. Commentary
    4. Original Articles
    5. Clinical Vignette
    6. Short Reports
    7. Case Report
    1. You have free access to this content
      Odanacatib: Location and timing are everything (pages 506–508)

      Sundeep Khosla

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1541

  3. Original Articles

    1. Top of page
    2. Perspective
    3. Commentary
    4. Original Articles
    5. Clinical Vignette
    6. Short Reports
    7. Case Report
    1. You have full text access to this OnlineOpen article
      Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys (pages 509–523)

      Patricia J Masarachia, Brenda L Pennypacker, Maureen Pickarski, Kevin R Scott, Gregg A Wesolowski, Susan Y Smith, Rani Samadfam, Jason E Goetzmann, Boyd B Scott, Donald B Kimmel and Le T Duong

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1475

    2. You have full text access to this OnlineOpen article
      Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey (pages 524–537)

      Tara Cusick, Charles M Chen, Brenda L Pennypacker, Maureen Pickarski, Donald B Kimmel, Boyd B Scott and Le T Duong

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1477

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      Interactions between extracellular signal-regulated kinase 1/2 and P38 Map kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity (pages 538–551)

      Chunxi Ge, Qian Yang, Guisheng Zhao, Hong Yu, Keith L Kirkwood and Renny T Franceschi

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.561

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      PlexinA2 mediates osteoblast differentiation via regulation of Runx2 (pages 552–562)

      Ji-Eun Oh, Hyung Joon Kim, Woo-Shin Kim, Zang Hee Lee, Hyun-Mo Ryoo, Soon Jung Hwang, Youngkyun Lee and Hong-Hee Kim

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1471

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      Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow (pages 563–574)

      X Lucas Lu, Bo Huo, Victor Chiang and X Edward Guo

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1474

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      WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production (pages 575–585)

      Martina Rauner, Nicola Stein, Maria Winzer, Claudia Goettsch, Jochen Zwerina, Georg Schett, Jörg HW Distler, Joachim Albers, Jochen Schulze, Thorsten Schinke, Martin Bornhäuser, Uwe Platzbecker and Lorenz C Hofbauer

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1488

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      Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region-specific changes in vascularization (pages 586–595)

      Ingrid J Poulton, Narelle E McGregor, Sueli Pompolo, Emma C Walker and Natalie A Sims

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1485

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      VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival (pages 596–609)

      Christa Maes, Elisa Araldi, Katharina Haigh, Richa Khatri, Riet Van Looveren, Amato J Giaccia, Jody J Haigh, Geert Carmeliet and Ernestina Schipani

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1487

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      The association between insulin levels and cortical bone: Findings from a cross-sectional analysis of pQCT parameters in adolescents (pages 610–618)

      Adrian Sayers, Debbie A Lawlor, Naveed Sattar and Jon H Tobias

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1467

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      Effect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: Results from the look AHEAD randomized trial (pages 619–627)

      Ann V Schwartz, Karen C Johnson, Steven E Kahn, John A Shepherd, Michael C Nevitt, Anne L Peters, Michael P Walkup, Amelia Hodges, Carrie C Williams and George A Bray, the Look AHEAD Research Group

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1483

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      Age determines longitudinal changes in body composition better than menopausal and bone status: The OFELY study (pages 628–636)

      Elisabeth Sornay-Rendu, Caroline Karras-Guillibert, Francoise Munoz, Bruno Claustrat and Roland D Chapurlat

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1469

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      Relationship of age to bone microstructure independent of areal bone mineral density (pages 637–644)

      Kristy M Nicks, Shreyasee Amin, Elizabeth J Atkinson, B Lawrence Riggs, L Joseph Melton III and Sundeep Khosla

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1468

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      Previous fractures at multiple sites increase the risk for subsequent fractures: The global longitudinal study of osteoporosis in women (pages 645–653)

      Stephen Gehlbach, Kenneth G Saag, Jonathan D Adachi, Fred H Hooven, Julie Flahive, Steven Boonen, Roland D Chapurlat, Juliet E Compston, Cyrus Cooper, Adolfo Díez-Perez, Susan L Greenspan, Andrea Z LaCroix, J Coen Netelenbos, Johannes Pfeilschifter, Maurizio Rossini, Christian Roux, Philip N Sambrook, Stuart Silverman, Ethel S Siris, Nelson B Watts and Robert Lindsay

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1476

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      QCT measures of bone strength at the thoracic and lumbar spine: The Framingham study (pages 654–663)

      Elizabeth J Samelson, Blaine A Christiansen, Serkalem Demissie, Kerry E Broe, Qiong Louie-Gao, L Adrienne Cupples, Benjamin J Roberts, Rajaram Manoharam, John D'Agostino, Thomas Lang, Douglas P Kiel and Mary L Bouxsein

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1482

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      Randomized controlled trial of a primary care–based screening program to identify older women with prevalent osteoporotic vertebral fractures: Cohort for skeletal health in Bristol and Avon (COSHIBA) (pages 664–671)

      Emma M Clark, Virginia Gould, Leigh Morrison, AE Ades, Paul Dieppe and Jon H Tobias

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1478

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      Reduced cortical bone compositional heterogeneity with bisphosphonate treatment in postmenopausal women with intertrochanteric and subtrochanteric fractures (pages 672–678)

      Eve Donnelly, Dennis S Meredith, Joseph T Nguyen, Brian P Gladnick, Brian J Rebolledo, Andre D Shaffer, Dean G Lorich, Joseph M Lane and Adele L Boskey

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.560

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      Esophageal and gastric cancer incidence and mortality in alendronate users (pages 679–686)

      Bo Abrahamsen, Michael Pazianas, Pia Eiken, R Graham G Russell and Richard Eastell

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1481

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      Relationship between bone mineral density changes with denosumab treatment and risk reduction for vertebral and nonvertebral fractures (pages 687–693)

      Matthew Austin, Yu-Ching Yang, Eric Vittinghoff, Silvano Adami, Steven Boonen, Douglas C Bauer, Gerolamo Bianchi, Michael A Bolognese, Claus Christiansen, Richard Eastell, Andreas Grauer, Federico Hawkins, David L Kendler, Beatriz Oliveri, Michael R McClung, Ian R Reid, Ethel S Siris, Jose Zanchetta, Cristiano AF Zerbini, Cesar Libanati and Steven R Cummings, for the FREEDOM Trial

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1472

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      Five years of denosumab exposure in women with postmenopausal osteoporosis: Results from the first two years of the FREEDOM extension (pages 694–701)

      Socrates Papapoulos, Roland Chapurlat, Cesar Libanati, Maria Luisa Brandi, Jacques P Brown, Edward Czerwiński, Marc-Antoine Krieg, Zulema Man, Dan Mellström, Sebastião C Radominski, Jean-Yves Reginster, Heinrich Resch, José A Román Ivorra, Christian Roux, Eric Vittinghoff, Matthew Austin, Nadia Daizadeh, Michelle N Bradley, Andreas Grauer, Steven R Cummings and Henry G Bone

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1479

    20. You have full text access to this OnlineOpen article
      Parathyroid hormone treatment improves the cortical bone microstructure by improving the distribution of type I collagen in postmenopausal women with osteoporosis (pages 702–712)

      Maria-Grazia Ascenzi, Vivian P Liao, Brittany M Lee, Fabrizio Billi, Hua Zhou, Robert Lindsay, Felicia Cosman, Jeri Nieves, John P Bilezikian and David W Dempster

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1497

  4. Clinical Vignette

    1. Top of page
    2. Perspective
    3. Commentary
    4. Original Articles
    5. Clinical Vignette
    6. Short Reports
    7. Case Report
    1. You have full text access to this OnlineOpen article
      Low bone mass and high material bone density in two patients with Loeys-Dietz syndrome caused by transforming growth factor beta receptor 2 mutations (pages 713–718)

      I Mouna Ben Amor, Thomas Edouard, Francis H Glorieux, Gilles Chabot, Marc Tischkowitz, Paul Roschger, Klaus Klaushofer and Frank Rauch

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1470

  5. Short Reports

    1. Top of page
    2. Perspective
    3. Commentary
    4. Original Articles
    5. Clinical Vignette
    6. Short Reports
    7. Case Report
    1. You have full text access to this OnlineOpen article
      Adverse events from calcium supplementation: Relationship to errors in myocardial infarction self-reporting in randomized controlled trials of calcium supplementation (pages 719–722)

      Joshua R Lewis, Kun Zhu and Richard L Prince

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1484

    2. You have full text access to this OnlineOpen article
      Lack of expression of SERPINF1, the gene coding for pigment epithelium-derived factor, causes progressively deforming osteogenesis imperfecta with normal type I collagen (pages 723–728)

      Giacomo Venturi, Alberto Gandini, Elena Monti, Luca Dalle Carbonare, Massimiliano Corradi, Monica Vincenzi, Maria Teresa Valenti, Maurizia Valli, Enrico Pelilli, Attilio Boner, Monica Mottes and Franco Antoniazzi

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1480

  6. Case Report

    1. Top of page
    2. Perspective
    3. Commentary
    4. Original Articles
    5. Clinical Vignette
    6. Short Reports
    7. Case Report
    1. You have full text access to this OnlineOpen article
      Fibrodysplasia ossificans progressiva: Middle-age onset of heterotopic ossification from a unique missense mutation (c.974G > C, p.G325A) in ACVR1 (pages 729–737)

      Michael P Whyte, Deborah Wenkert, Jennifer L Demertzis, Edward F DiCarlo, Erica Westenberg and Steven Mumm

      Article first published online: 21 FEB 2012 | DOI: 10.1002/jbmr.1473

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