Plasmapheresis for hemolytic crisis and impending acute liver failure in Wilson disease
Article first published online: 19 SEP 2007
Copyright © 2007 Wiley-Liss, Inc.
Journal of Clinical Apheresis
Volume 22, Issue 5, pages 295–298, October 2007
How to Cite
Asfaha, S., Almansori, M., Qarni, U. and Gutfreund, K. S. (2007), Plasmapheresis for hemolytic crisis and impending acute liver failure in Wilson disease. J. Clin. Apheresis, 22: 295–298. doi: 10.1002/jca.20140
- Issue published online: 12 OCT 2007
- Article first published online: 19 SEP 2007
- Manuscript Accepted: 7 JUN 2007
- Manuscript Received: 15 DEC 2006
- hemolytic anemia;
- acute liver failure;
- continuous veno-venous hemodialysis;
- molecular adsorbents and recirculating system
Wilsonian crisis is fatal unless copper removal is initiated early and liver transplantation is performed for patients that fulfill criteria for a poor outcome. We report a patient presenting with severe hemolysis and impending acute liver failure that made a rapid recovery with prompt initiation of plasmapheresis and chelation therapy. Rapid copper removal by plasmapheresis alleviated hemolysis and liver injury. A review of the literature was performed examining the use of plasmapheresis and albumin dialysis with continuous veno-venous hemodialysis or molecular adsorbents and recirculating system. J. Clin. Apheresis, 2007. © 2007 Wiley-Liss, Inc.