Brief Report

Therapeutic plasma exchange in Streptococcus pneumoniae-associated hemolytic uremic syndrome: A case report

  1. Melissa L. Petras1,*,
  2. Nancy M. Dunbar1,2,
  3. James J. Filiano3,
  4. Matthew S. Braga3,
  5. Michael C. Chobanian4,
  6. Zbigniew M. Szczepiorkowski1,2

Article first published online: 3 FEB 2012

DOI: 10.1002/jca.21208

Additional Information

How to Cite

Petras, M. L., Dunbar, N. M., Filiano, J. J., Braga, M. S., Chobanian, M. C. and Szczepiorkowski, Z. M. (2012), Therapeutic plasma exchange in Streptococcus pneumoniae-associated hemolytic uremic syndrome: A case report. J. Clin. Apheresis. doi: 10.1002/jca.21208

Author Information

  1. 1

    Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

  2. 2

    Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

  3. 3

    Department of Pediatrics, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

  4. 4

    Department of Transplant Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

*One Medical Center Drive, Lebanon, NH 03756-0001, USA

Publication History

  1. Article first published online: 3 FEB 2012
  2. Manuscript Accepted: 22 DEC 2011
  3. Manuscript Received: 3 AUG 2011

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Keywords:

  • streptococcal HUS;
  • atypical;
  • TPE;
  • T antigen

Abstract

Streptococcus pneumoniae-associated hemolytic uremic syndrome (pHUS) is an atypical form of HUS associated with microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. Although less common than diarrhea-associated HUS, incidence appears to be increasing. We report a case of a child with pHUS who underwent a course of therapeutic plasma exchange (TPE) and had complete recovery. This report adds to the existing literature supporting TPE in cases of pHUS. J. Clin. Apheresis, 2012. © 2012 Wiley Periodicals, Inc.

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