A retrospective study of autologous stem cell mobilization to guide an immediate salvage protocol using plerixafor for patients who mobilize stem cells poorly
Version of Record online: 11 MAR 2013
Copyright © 2013 Wiley Periodicals, Inc.
Journal of Clinical Apheresis
Volume 28, Issue 5, pages 378–380, October 2013
How to Cite
Hay, A. E., Lawrie, A., Robinson, N., Dong, B. and Culligan, D. J. (2013), A retrospective study of autologous stem cell mobilization to guide an immediate salvage protocol using plerixafor for patients who mobilize stem cells poorly. J. Clin. Apheresis, 28: 378–380. doi: 10.1002/jca.21274
- Issue online: 11 OCT 2013
- Version of Record online: 11 MAR 2013
- Manuscript Accepted: 27 JAN 2013
- Manuscript Revised: 18 JAN 2013
- Manuscript Received: 17 AUG 2012
The addition of plerixafor to G-CSF decreases the risk of failed stem cell collection, but at considerable extra cost. Using a logistic regression model based on 354 autologous mobilizations, we have identified a local minimum peripheral blood CD34 count at which the probability of a successful collection is 50%. This seems an appropriate CD34 count at which to add immediate salvage plerixafor. J. Clin. Apheresis 28:378–380, 2013. © 2013 Wiley Periodicals, Inc.