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A retrospective study of autologous stem cell mobilization to guide an immediate salvage protocol using plerixafor for patients who mobilize stem cells poorly

Authors


Correspondence to: Dr. Dominic Culligan, ANCHOR Unit, Department of Haematology, Aberdeen Royal Infirmary, Foresterhill Road, Aberdeen, Scotland AB25 2ZN. E-mail: dominic.culligan@nhs.net

Abstract

The addition of plerixafor to G-CSF decreases the risk of failed stem cell collection, but at considerable extra cost. Using a logistic regression model based on 354 autologous mobilizations, we have identified a local minimum peripheral blood CD34 count at which the probability of a successful collection is 50%. This seems an appropriate CD34 count at which to add immediate salvage plerixafor. J. Clin. Apheresis 28:378–380, 2013. © 2013 Wiley Periodicals, Inc.

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