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Prospect
Quantitative assessment of tumor oxygen dynamics: Molecular imaging for prognostic radiology
Article first published online: 16 JAN 2003
DOI: 10.1002/jcb.10404
Copyright © 2002 Wiley-Liss, Inc.
Issue
1097-4644/asset/cover.gif?v=1&s=c55ee036b3038496cb712d572571012ddd7c366c "Journal of Cellular Biochemistry")
Journal of Cellular Biochemistry
Supplement: Molecular Imaging
Volume 87, Issue Supplement 39, pages 45–53, 2002
Additional Information
How to Cite
Mason, R. P., Ran, S. and Thorpe, P. E. (2002), Quantitative assessment of tumor oxygen dynamics: Molecular imaging for prognostic radiology. J. Cell. Biochem., 87: 45–53. doi: 10.1002/jcb.10404
Publication History
- Issue published online: 16 JAN 2003
- Article first published online: 16 JAN 2003
- Manuscript Accepted: 8 OCT 2002
- Manuscript Received: 4 OCT 2002
Funded by
- The National Cancer Institute. Grant Numbers: RO1 CA74951, CA54168, CA79515
- Cancer Imaging Program. Grant Number: P20 CA 86354
- NIH BRTP Facility. Grant Number: P41-RR02584
- Abstract
- Article
- References
- Cited By
Keywords:
- magnetic resonance imaging;
- hexafluorobenzene;
- oxygen;
- tumor;
- tissue factor;
- antibody targeting
Abstract
One of the fundamental molecules governing the survival of mammalian cells is oxygen. Oxygen has gained particular significance in tumor developmental biology and oncology. An increasingly diverse array of methods is now available to characterize tumor oxygenation. This Prospect will consider a new method, Fluorocarbon Relaxometry using Echo planar imaging for Dynamic Oxygen Mapping (FREDOM), which we have recently developed for oximetry, examine application to a specific therapeutic example and place this technique in the context of other approaches. J. Cell. Biochem. Suppl. 39: 45–53, 2002. © 2002 Wiley-Liss, Inc.