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jcb_22238_sm_SupplFig.tif6530KSupplementary Figure. Negative controls for immunohistochemistry analysis. Human normal cartilage sections were used as positive controls for collagen type II (COL2) and aggrecan C-20. Human osteoarthritis (OA) cartilage sections were used as positive controls for matrix metalloproteinase-13 (MMP-13) and collagen type X (COLX). Human skin sections were used as positive controls for collagen type I (COL1). The negative control were sections of spheroids containing chondrocyte-like cells engineered from CD105+-mesenchymal stem cells (CD105+-MSCs) from normal synovial membranes incubated with mouse serum only (Magnification 20x).

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