Article

Identification of microRNAs regulated by activin A in human embryonic stem cells†‡§

  1. Zong-Yun Tsai1,2,
  2. Sher Singh3,
  3. Sung-Liang Yu4,
  4. Li-Pin Kao5,
  5. Bo-Zhi Chen5,
  6. Bing-Ching Ho4,
  7. Pan-Chyr Yang6,
  8. Steven Shoei-Lung Li2,5,*

Article first published online: 2 NOV 2009

DOI: 10.1002/jcb.22385

Issue

Journal of Cellular Biochemistry

Journal of Cellular Biochemistry

Volume 109, Issue 1, pages 93–102, 1 January 2010

Additional Information

How to Cite

Tsai, Z.-Y., Singh, S., Yu, S.-L., Kao, L.-P., Chen, B.-Z., Ho, B.-C., Yang, P.-C. and Li, S. S.-L. (2010), Identification of microRNAs regulated by activin A in human embryonic stem cells. J. Cell. Biochem., 109: 93–102. doi: 10.1002/jcb.22385

Author Information

  1. 1

    Department of Medicinal and Applied Chemistry, College of Life Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan

  2. 2

    Stem Cell Laboratory, Center of Excellence for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan

  3. 3

    Department of Life Science, College of Science, National Taiwan Normal University, Taipei 116, Taiwan

  4. 4

    Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan

  5. 5

    Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan

  6. 6

    Department of Internal Medicine, National Taiwan University College of Medicine, Taipei 100, Taiwan

*Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

  1. †

    Authors' contributions: ZYT cultured and characterized T3MF, T3CM, and T3BA cells, as well as did part of data analyses. SS did bioinformatic analyses. S-LY supervised the determination of both miRNAs and mRNAs. L-PK prepared RNA samples. BZC maintained T3MF cells. BCH did luciferase assay. PCY directed the Microarray Core Facility for Genomic Medicine of National Taiwan University College of Medicine where the analyses of miRNAs and mRNAs were done. SSLL designed the experiments, analyzed results, and wrote the manuscript.

  2. ‡

    Database and accession number: The original data obtained from Affymetrix human genome U133 plus 2.0 GeneChip have been deposited to NCBI database, and the GEO series number is GSE16910.

  3. §

    Zong-Yun Tsai and Sher Singh contributed equally to this work.

  4. The authors declare no competing financial interests.

Publication History

  1. Issue published online: 21 DEC 2009
  2. Article first published online: 2 NOV 2009
  3. Manuscript Accepted: 21 SEP 2009
  4. Manuscript Received: 9 JUL 2009

Funded by

  • National Science Council of Taiwan. Grant Number: NSC-95/96/97-3112-B-037-02
  • Center of Excellent for Environmental Medicine Project. Grant Number: KMU-EM-97-1.3c

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