Cellular and molecular effects of resveratrol in health and disease

Authors

  • Wei Yu,

    1. Department of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, People's Republic of China
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  • Yu-Cai Fu,

    Corresponding author
    1. Laboratory of Cell Senescence, Shantou University Medical College, Shantou 515041, People's Republic of China
    • Laboratory of Cell Senescence, Shantou University Medical College, No. 22, xin-ling Road, Shantou 515041, People's Republic of China.
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  • Wei Wang

    Corresponding author
    1. Department of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, People's Republic of China
    • Department of Cardiology, The First Affiliated Hospital of Shantou University Medical College, No. 57, chang-ping Road, Shantou 515041, People's Republic of China.
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Abstract

Resveratrol, a natural polyphenol abundantly found in grape skins and red wine, possesses diverse biochemical and physiological actions, including anti-inflammatory, anti-oxidation, anti-proliferation and promotion of differentiation, and chemopreventive effects. Recently, it is attracting increased attention due to its health benefits, especially in common age-related diseases such as cardiovascular disease, cancer, type 2 diabetes, and neurological conditions. In this review, we discuss the latest cellular and molecular findings that account for the beneficial actions of resveratrol. J. Cell. Biochem. 113: 752–759, 2012. © 2011 Wiley Periodicals, Inc.

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