Article

HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins

  1. Kwang Hwa Jung1,2,
  2. Ji Heon Noh1,2,
  3. Jeong Kyu Kim1,2,
  4. Jung Woo Eun1,2,
  5. Hyun Jin Bae1,2,
  6. Hong Jian Xie1,2,
  7. Young Gyoon Chang1,2,
  8. Min Gyu Kim1,2,
  9. Hanna Park1,2,
  10. Jung Young Lee1,2,
  11. Suk Woo Nam1,2,*

Article first published online: 10 APR 2012

DOI: 10.1002/jcb.24090

Issue

Journal of Cellular Biochemistry

Journal of Cellular Biochemistry

Volume 113, Issue 6, pages 2167–2177, June 2012

Additional Information

How to Cite

Jung, K. H., Noh, J. H., Kim, J. K., Eun, J. W., Bae, H. J., Xie, H. J., Chang, Y. G., Kim, M. G., Park, H., Lee, J. Y. and Nam, S. W. (2012), HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins. J. Cell. Biochem., 113: 2167–2177. doi: 10.1002/jcb.24090

Author Information

  1. 1

    Department of Pathology, College of Medicine and Functional RNomics Research Center, The Catholic University of Korea, Banpo-dong, Seocho-gu, Seoul, Korea

  2. 2

    Functional RNomics Research Center, The Catholic University of Korea, Seoul, Korea

*Department of Pathology, College of Medicine and Functional RNomics Research Center, The Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Korea.

Publication History

  1. Issue published online: 10 APR 2012
  2. Article first published online: 10 APR 2012
  3. Accepted manuscript online: 3 FEB 2012 01:53PM EST
  4. Manuscript Accepted: 27 JAN 2012
  5. Manuscript Received: 6 OCT 2011

Funded by

  • Basic Science Research and Public Welfare & Safety programs through National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology. Grant Numbers: 2009-0072504, 2010-0020764

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FilenameFormatSizeDescription
jcb_24090_sm_SupplFigS1.tif1446KSupplementary Figure S1. Endogenous expression of HDACs in NCI-H358 cells measured by quantitative real-time reverse transcriptase PCR. HDAC mRNA levels were normalized against GAPDH and graph bars show the relative expression of HDACs in NCI-H358 cells. Each experiment was performed in triplicate and repeated twice with the same results. Error bars show mean and SD.
jcb_24090_sm_SupplTab1.doc48KSupplementary Table 1. Primers used for mRNA amplification by the quantitative real time RT-PCR
jcb_24090_sm_SupplTab2.doc64KSupplementary Table 2. Primary antibodies used for immunoblotting.

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